Results 71 to 80 of about 1,113,885 (299)

Histologic and histomorphometric analysis of bone regeneration with bovine grafting material after 24 months of healing. A case report [PDF]

, 2018
Anorganic bovine bone mineral matrix (ABBMM) has been reported to have osteoconductive properties and no inflammatory or adverse responses when used as grafting material in sinus augmentation procedures.
Belleggia, Fabrizio, DeVillier, Patricia, Guarnieri, Renzo, Testarelli, Luca   +3 more
core   +1 more source

Joint and individual analysis of breast cancer histologic images and genomic covariates [PDF]

, 2020
A key challenge in modern data analysis is understanding connections between complex and differing modalities of data. For example, two of the main approaches to the study of breast cancer are histopathology (analyzing visual characteristics of tumors ...
Calhoun, Benjamin C., Carmichael, Iain, Couture, Heather D., Geradts, Joseph, Hannig, Jan, Hoadley, Katherine A., Marron, J. S., Niethammer, Marc, Olsson, Linnea, Perou, Charles M., Troester, Melissa A.   +10 more
core   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Histological staining methods preparatory to laser capture microdissection significantly affect the integrity of the cellular RNA

BMC Genomics, 2006
Background Gene expression profiling by microarray analysis of cells enriched by laser capture microdissection (LCM) faces several technical challenges.
Li Ming-Chung, Shih Joanna H, Owens James D, Wang Hongyang, Bonner Robert F, Mushinski J Frederic   +5 more
doaj   +1 more source

Modern Methods of Histological Examination

Texas Journal of Medical Science, 2023
This article provides information about histology, the most modern methods of histological examination that are being tested and used in the current age of technology.
null Sobirova Dildora Ravshanovna, null Azizova Feruza Khusanovna, null Otajonova Aziza Nigmatullayevna, null Surayyo Habibullayevna Ishandzhanova,, null Tursunmetov Ibodulla Roziboyevich,, null Makhmudova Shakhlo Ismatullayevna   +5 more
openaire   +1 more source

A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]

, 2018
Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro, Frezzotti, Francesca, Giacomelli, Laura, Graves, Claire Elizabeth, Metere, Alessio, Pietraforte, Donatella, Vergine, Massimo   +6 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Diagnostic accuracy of sonohysterography vs hysteroscopy in benign uterine endocavitary findings [PDF]

, 2015
OBJECTIVE: To compare diagnostic accuracy of sonohysterography vs hysteroscopy in patients with benign uterine endocavitary findings. PATIENTS AND METHODS: This retrospective study evaluated 202 patients submitted to sonohysterography after transvaginal ...
Bianchi, Paola, Caserta, Donatella, Catalano, Angelica, Cozza, Giuliana, DI PROPERZIO, Matilde, Frega, Antonio, Gentile, M, Manzara, F, Marziani, Rosalia, Milazzo, Gn, Schimberni, Mauro, Torcia, Francesco, Zinna, M   +12 more
core  

Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND) [PDF]

, 2018
A key challenge in medical imaging is determining a precise correspondence between image properties and tissue microstructure. This comparison is hindered by disparate scales and resolutions between medical imaging and histology.
Ball, G, Edwards, A D, Jones, M, So, P-W, Stolp, H B, Thornton, C, Tournier, J-D   +6 more
core   +6 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source