Results 71 to 80 of about 823,186 (305)

Histological effects of chronic administration of Phyllanthus amarus on the kidney of adult Wistar rat [PDF]

, 2010
Background: Phyllanthus amarus is commonly used for treatment such as in gastro, urogenital diseases and infection. However, it is speculated to have some toxic effects such as renal tubular damage.
Nwose, Ezekiel Uba, Adjene, Josiah Obaghwarhievwo   +1 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Quantitative methods in neuropathology [PDF]

, 2010
The last decade has seen a considerable increase in the application of quantitative methods in the study of histological sections of brain tissue and especially in the study of neurodegenerative disease.
Armstrong, Richard A.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Methods in Plant Histology [PDF]

Science, 1915
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openaire   +2 more sources

Segmentation and 3D Reconstruction of Animal Tissues in Histological Images [PDF]

, 2015
: Histology is considered the "gold standard " to access anatomical infor-mation at a cellular level. In histological studies, tissue samples are cut into very thin sections, stained, and observed under a microscope by a specialist.
Liliana Azevedo, Augusto M. R. Faustino, João Manuel R. S. Tavares   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Inquisition of the Human Intervertebral Disk Histopathology with the Use of Two Histological Staining Methods

Global Spine Journal, 2012
Introduction Chronic low back pain (LBP) affects over 10% of the adult population resulting in profound decreases in the quality of life. The intervertebral disk (IVD) is prone to degeneration which may contribute toLBP.
C. E. Ferland, Z. S. Tabatabaei Shafiei, R. Gawri, L. Haglund, J. A. Ouellet, L. S. Stone   +5 more
doaj   +1 more source

Histological staining methods preparatory to laser capture microdissection significantly affect the integrity of the cellular RNA

BMC Genomics, 2006
Background Gene expression profiling by microarray analysis of cells enriched by laser capture microdissection (LCM) faces several technical challenges.
Li Ming-Chung, Shih Joanna H, Owens James D, Wang Hongyang, Bonner Robert F, Mushinski J Frederic   +5 more
doaj   +1 more source