Results 271 to 280 of about 2,155,308 (355)

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

Advanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez   +15 more
wiley   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

Non-Wilms Renal Tumours in Children: The Republic of Ireland Experience. [PDF]

Children (Basel)
Hughes K, Lee C, Capra M, Pears J, Owens C, McDermott M, O'Sullivan M, Paran S, Fernandez-Pineda I.   +8 more
europepmc   +1 more source

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

Advanced Materials, EarlyView.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng, Isaak Decoene, Hanna Svitina, Ioannis Papantoniou   +3 more
wiley   +1 more source

Registry Study of the Working Group on Cervical Pathology and Colposcopy (AGCPC) on the Diagnostic Algorithm for the New Cervical Cancer Screening - Persistent HPV Infections and Squamous Cell Lesions: Evaluation of over 10000 Patients. [PDF]

Geburtshilfe Frauenheilkd
Henes M, Mann E, Hirchenhain C, Kentner A, Selgrad C, Hampl M, Keyver-Paik MD, Quaas J, Gallwas J, Koßagk C, Helbig M, Gaß P, Jakubek F, Klar M, Henes L, Küppers V.   +15 more
europepmc   +1 more source

Localized Temperature Monitoring in Mouse Brain during Light Delivery via a Non‐Planar Tapered Fiber‐Integrated µRTD Sensor

Advanced Materials, EarlyView.
We report a multifunctional tapered optical fiber integrating a conformal micro‐resistance temperature detector (µRTD) for local, real‐time thermometry during optical stimulation. The platform combines light‐delivery and temperature sensing within a minimally invasive footprint, enabling detection of sub‐degree cortical heating under representative ...
Antonio Balena, Marco Bianco, Barbara Spagnolo, Muhammad Fayyaz Kashif, Alberto Bramati, Massimo De Vittorio, Ferruccio Pisanello   +6 more
wiley   +1 more source

Multimodal contrastive learning for non-invasive chondroid bone tumor classification and grading using radiographs. [PDF]

BMC Med Imaging
Hua P, Sin JM, Henderson ER, Ha J, Kerr DA, Hassanpour S.   +5 more
europepmc   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, EarlyView.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source

Preoperative (Neoadjuvant) Combined Chemoradiotherapy in the Management of Localized Soft Tissue Sarcoma: A Retrospective Study. [PDF]

Cancers (Basel)
Siontis BL, Stergiopoulos GM, Jebastin Thangaiah J, Ho TP, Ahmed SK, Grotz TE, Houdek MT, Folpe AL, Okuno SH, Robinson SI.   +9 more
europepmc   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source