Serum proteomics mirrors the histopathological changes underlying different etiologies of primary mitral valve disease. [PDF]
Garcia-Peña A +12 more
europepmc +1 more source
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source
Chronic Thermal Stress During Early Zebrafish (Danio rerio) Development Induces Morphological, Molecular, and Liver Histopathological Changes. [PDF]
Adzijovski M +4 more
europepmc +1 more source
Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre +12 more
wiley +1 more source
Histopathological Changes Following Bromelain-Based Enzymatic Debridement (NexoBrid<sup>®</sup>): A Comprehensive Systematic Review of Preclinical and Clinical Evidence. [PDF]
Avadanei-Luca S +7 more
europepmc +1 more source
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source
Histopathological Changes of the Corticospinal Tract Following Hemorrhagic and Ischemic Stroke. [PDF]
Kollai S +4 more
europepmc +1 more source
Normal Histopathology: Minimal Change Disease
openaire +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Histopathological Changes as a Predictor of Fatal Outcome in Patients With Drug-Induced Liver Injury. [PDF]
Weber S +9 more
europepmc +1 more source

