Results 141 to 150 of about 713,518 (369)

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

open access: yesAdvanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li   +8 more
wiley   +1 more source

Investigation of Perognathus as an experimental organism for research in space biology Progress report, 1 Jul. - 30 Sep. 1965 [PDF]

open access: yes
Histopathology of pocket mouse intestine mucous after irradiation - growth and development data on laboratory pocket ...
Gambino, J. J., Lindberg, R. G.
core   +1 more source

Mitosis domain generalization in histopathology images - The MIDOG challenge [PDF]

open access: yesMedical Image Anal., 2022
M. Aubreville   +34 more
semanticscholar   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

open access: yesAdvanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu   +8 more
wiley   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

open access: yesAdvanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen   +22 more
wiley   +1 more source

Cutaneous eruption after commencing baricitinib for rheumatoid arthritis

open access: yesJEADV Clinical Practice
This case report describes a 64‐year‐old physician with seronegative rheumatoid arthritis (RA) who was treated with baricitinib after failing multiple other therapies.
Rosemary Akinbisehin   +3 more
doaj   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu   +14 more
wiley   +1 more source

Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning

open access: yesNature Medicine, 2018
N. Coudray   +8 more
semanticscholar   +1 more source

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