Results 151 to 160 of about 713,518 (369)

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Correlation of Fluorescent Antibody, Histopathology, and Culture on Tissues from 372 Animals Examined for Histoplasmosis and Blastomycosis [PDF]

, 1965
Billie M. Porter, Barbara K. Comfort, Robert W. Menges, R. T. Habermann, C. D. Smith   +4 more
openalex   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series

The Lancet, 2020
B. T. Bradley, Heather Maioli, R. Johnston, Irfan Chaudhry, S. Fink, Hao-dong Xu, Behzad Najafian, G. Deutsch, J. Lacy, T. Williams, Nicole Yarid, D. Marshall   +11 more
semanticscholar   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

The Effect of Fibrosis on DNA Yield from Formalin Fixed Paraffin Embedded Tissues

Pakistan Armed Forces Medical Journal
Objective: To report the effect of fibrosis on yield of Deoxyribonucleic Acid extraction from Formalin-Fixed Paraffin-Embedded tissue. Study Design: Cross sectional study.
Muhammad Naveed, Hassan Tariq, Asma Gul, Natasha Arzo, Muhammad Hussain, Sumaira Buksh   +5 more
doaj   +1 more source

Generative Adversarial Networks for Stain Normalisation in Histopathology [PDF]

, 2023
Jack Breen, Kieran Zucker, Katie Allen, Nishant Ravikumar, Nicolas M. Orsi   +4 more
openalex   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Kidney Histopathology and Prediction of Kidney Failure: A Retrospective Cohort Study

, 2020
Michael T. Eadon, Tae-Hwi Schwantes-An, Carrie L. Phillips, Anna Roberts, Colin V. Greene, Ayman Hallab, Kyle Hart, Sarah N. Lipp, Claudio Perez-Ledezma, Khawaja O. Omar, Katherine J. Kelly, Sharon M. Moe, Pierre C. Dagher, Tarek M. El‐Achkar, Ranjani N. Moorthi   +14 more
openalex   +2 more sources

Book Review: A Colour Atlas of Thymus and Lymph Node Histopathology with Ultrastructure [PDF]

, 1982
Arnold Levene
openalex   +1 more source