Results 301 to 310 of about 713,518 (369)

Spectral entropy variability of intraoperative electrocorticography predicts outcome after epilepsy surgery in people with focal cortical dysplasia

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy surgery in people with focal cortical dysplasia (FCD) requires accurate removal of all epileptogenic tissue, and outcome is difficult to predict. We explored whether spectral entropy, a fast computable electroencephalographic (EEG) feature, could estimate epileptic activity in intraoperative electrocorticography (ioECoG) and
Eline V. Schaft   +53 more
wiley   +1 more source

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

open access: yesEpilepsia Open, EarlyView.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen   +24 more
wiley   +1 more source

Diagnostic performance of neuroimaging modalities for epileptogenic focus localization: A systematic review

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Accurate localization of epileptogenic foci remains of significant importance for surgical planning in drug‐resistant epilepsy. Multiple neuroimaging modalities are available; however, their comparative diagnostic performance lacks comparative detailed synthesis.
Mustafa S. Alhasan   +12 more
wiley   +1 more source

Distinct medial temporal volumetric signatures in extra‐medial temporal lobe lesional epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To quantify amygdala and hippocampal volumetric asymmetries in patients with drug‐resistant epilepsy (DRE) and extra‐medial temporal lesions (EMTLs) and to assess the prevalence of structural alterations relative to drug‐resistant temporal lobe epilepsy (TLE), extratemporal lobe epilepsy (ETLE), and healthy individuals.
Yonatan Serlin   +7 more
wiley   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha   +27 more
wiley   +1 more source

Sleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (
Mohammad F. Khazali   +14 more
wiley   +1 more source

Diagnostic Performance of Line-Field Confocal Optical Coherence Tomography for Basal Cell Carcinoma: A Prospective Study. [PDF]

open access: yesCancers (Basel)
Orte Cano C   +21 more
europepmc   +1 more source

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