Results 301 to 310 of about 713,518 (369)
Spectral entropy variability of intraoperative electrocorticography predicts outcome after epilepsy surgery in people with focal cortical dysplasia
Epilepsia, EarlyView.Abstract Objective
Epilepsy surgery in people with focal cortical dysplasia (FCD) requires accurate removal of all epileptogenic tissue, and outcome is difficult to predict. We explored whether spectral entropy, a fast computable electroencephalographic (EEG) feature, could estimate epileptic activity in intraoperative electrocorticography (ioECoG) and Eline V. Schaft, Sem Hoogteijling, Dongqing Sun, Cyrille H. Ferrier, Pieter van Eijsden, Wim M. Otte, Galia Anguelova, Nick F. Ramsey, Maryse A. van't Klooster, Maeike Zijlmans, on behalf of the RESPect database study group, Charlotte van Asch, Lydia van de Berg, Dorien van Blooijs, Kim Boshuisen, Mireille Bourez, Kees Braun, Jan Willem Dankbaar, Matteo Demuru, Pieter van Eijsden, Cyrille Ferrier, Tineke Gebbink, Fernando Gomez‐Acebo Ruiz, Peter Gosselaar, Kimberley Grasmeijer, Renate van Griethuysen, Jiaojiao Guo, Irene Heijink, Monique Hobbelink, Friso Hoefnagels, Sem Hoogteijling, Geertjan Huiskamp, Sarah Jacobs, Floor Jansen, Susanne Jelsma, Nicole van Klink, Merel Koopmans, Frans Leijten, Wouter Maathuis, Mariska Mantione, Angelika Muhlebner, Brechje Olgers, Janine van Ophorst, Miranda Postma, Sandra van der Salm, Eline Schaft, Anniek van Schaik, Monique van Schooneveld, Dongqing Sun, Ziyi Wang, Martine van Zandvoort, Eva Zuidhoek, Willemiek Zweiphenning, Jack Zwemmer +53 morewiley +1 more sourceMultimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab
Epilepsia Open, EarlyView.Abstract Objective
We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra +24 morewiley +1 more sourceDiagnostic performance of neuroimaging modalities for epileptogenic focus localization: A systematic review
Epilepsia Open, EarlyView.Abstract Objective
Accurate localization of epileptogenic foci remains of significant importance for surgical planning in drug‐resistant epilepsy. Multiple neuroimaging modalities are available; however, their comparative diagnostic performance lacks comparative detailed synthesis.Mustafa S. Alhasan, Mohammed Khalil, Ayman S. Alhasan, Ahmed Najjar, Yasir Hassan Elhassan, Abdullah Almaghraby, Omar Alharthi, Seham Hamoud, Muhammed Amir Essibayi, Fabricio Feltrin, Sumit Singh, James Milburn, Ahmed Y. Azzam +12 morewiley +1 more sourceDistinct medial temporal volumetric signatures in extra‐medial temporal lobe lesional epilepsy
Epilepsia Open, EarlyView.Abstract Objective
To quantify amygdala and hippocampal volumetric asymmetries in patients with drug‐resistant epilepsy (DRE) and extra‐medial temporal lesions (EMTLs) and to assess the prevalence of structural alterations relative to drug‐resistant temporal lobe epilepsy (TLE), extratemporal lobe epilepsy (ETLE), and healthy individuals.Yonatan Serlin, Bijal Patel, Elena Hayday, Alexandrea Kilgore‐Gomez, Tianxia Wu, Shareena A. Rahman, William H. Theodore, Sara K. Inati +7 morewiley +1 more sourceAreas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE
Epilepsia Open, EarlyView.Abstract Objective
To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods
This position paper was developed through a structured collaborative process involving patient ...Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou +27 morewiley +1 more sourceSleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia
Epilepsia Open, EarlyView.Abstract Objective
Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (Mohammad F. Khazali, Nina Schwoon, Armin Brandt, Matthias Dümpelmann, Yiwen Li Hegner, Nicolas Roehri, Dirk‐Matthias Altenmüller, Victoria San Antonio‐Arce, Peter C. Reinacher, Julia M. Nakagawa, Soroush Doostkam, Theo Demerath, Horst Urbach, Andreas Schulze‐Bonhage, Marcel Heers +14 morewiley +1 more sourceDiagnostic Performance of Line-Field Confocal Optical Coherence Tomography for Basal Cell Carcinoma: A Prospective Study. [PDF]
Cancers (Basel)Orte Cano C, Sanak D, Lenoir C, Diet G, Fontaine M, Boussingault L, Mtimet L, Aktas D, Rusu S, Trepant AL, Palmisano G, Di Stefani A, Cinotti E, Tognetti L, Pérez-Anker J, Peris K, Rubegni P, Puig S, Malvehy J, Perrot JL, Del Marmol V, Suppa M. +21 moreeuropepmc +1 more source