Results 51 to 60 of about 12,226 (182)

Challenging granulomatous differential diagnosis of CNS lesions in a 75-year-old patient with indolent lymphoma

Frontiers in Immunology
We report here on a patient with concomitant indolent lymphoma who showed a rapid progressive deterioration of his general condition and emerging neurological symptoms.
Lorenz Thurner, Ketevani Melivadze, Jakob Matschke, Theodoros Topalidis, Armin Bachhuber, Tilman Speicher, Florian Rosar, Udo Reischl, Wolfgang Tränkenschuh, Bettina Friesenhahn-Ochs, Peter Fries, Sören L. Becker, Octavian Fleser   +12 more
doaj   +1 more source

The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1

Molecular Microbiology, Volume 125, Issue 5, Page 389-411, May 2026.
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen, Samuel Plante, Berthy Mbuya, Simon Labbé   +3 more
wiley   +1 more source

Histoplasmosis in patients living with HIV in Europe: review of literature

Frontiers in Microbiology
Histoplasma capsulatum (var. capsulatum Hcc and duboisii Hcd), is a dimorphic fungus that causes histoplasmosis. It usually affects people coming from endemic areas, causing a variety of clinical manifestations up to progressive disseminated ...
Dimitra Kontogiannis, Andrea Di Lorenzo, Drieda Zaçe, Domenico Benvenuto, Martina Moccione, Gianmarco Muratore, Maria L. Giacalone, Giulia Montagnari, Laura Carnevale, Tiziana Mulas, Luigi Coppola, Laura Campogiani, Loredana Sarmati, Loredana Sarmati, Marco Iannetta, Marco Iannetta   +15 more
doaj   +1 more source

Invasive Fungal Infections After Intestine Transplantation: Epidemiology and Outcomes

Mycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Invasive fungal infections (IFIs) represent a major complication after intestine transplantation, with reported incidence rates between 40% and 49%. These infections are associated with high morbidity and allograft loss. This study evaluates the impact of post‐transplant IFIs on graft outcomes in intestine transplant recipients ...
Mayyadah H. Alabdely, Jessica Lum, Blanca E. Gonzalez, Masato Fujiki, Zachary A. Yetmar   +4 more
wiley   +1 more source

Late Onset Telomere Biology Disorder Presenting With Pancytopenia, Immune Dysregulation, Interstitial Lung Disease and Alopecia

American Journal of Hematology, Volume 101, Issue 6, Page 1196-1200, June 2026.
Bo A. Wan, Hamish Nicolson, Heather A. Leitch, Ryan J. Stubbins, Luke Y. C. Chen, Timothy Murray, Amy Trottier, Anthony Gador   +7 more
wiley   +1 more source

Histoplasma antigen detection: A laboratory-based retrospective review of routine testing from 2021 to 2023

Biomédica: revista del Instituto Nacional de Salud
Introduction. Progressive disseminated histoplasmosis is associated with high mortality in people with advanced HIV (Human Immunodeficiency Virus) disease or severe immunosuppression.
Juan Carlos Gómez, Diego H. Cáceres
doaj   +1 more source

Genome Sequences Reveal Cryptic Speciation in the Human Pathogen Histoplasma capsulatum

mBio, 2017
Histoplasma capsulatum is a pathogenic fungus that causes life-threatening lung infections. About 500,000 people are exposed to H. capsulatum each year in the United States, and over 60% of the U.S. population has been exposed to the fungus at some point
Victoria E. Sepúlveda, Roberto Márquez, David A. Turissini, William E. Goldman, Daniel R. Matute   +4 more
doaj   +1 more source

Elevated carbon dioxide enhances the growth and reduces the antifungal susceptibility of Histoplasma capsulatum

Microbiology Spectrum
Histoplasma capsulatum is a thermally dimorphic fungal pathogen. It causes approximately 500,000 infections annually in the United States. Histoplasma is present as avirulent mycelia in the soil and transforms into pathogenic yeasts at the human body ...
Qian Shen, Kelsey Steinmetz
doaj   +1 more source

Updates in the Language of Histoplasma Biodiversity

mBio, 2018
In a recent article, Sepúlveda et al. (mBio 8:e01339-17, 2017, https://doi.org/10.1128/mBio.01339-17) investigated the genetic structure and evolutionary history of the human pathogen Histoplasma.
Pierre Gladieux
doaj   +1 more source

Revealing pathogenesis-associated metabolites in Histoplasma capsulatum through comprehensive metabolic profiling

mSystems
During infection, Histoplasma capsulatum yeasts interact with a variety of phagocytic cells, where macrophages represent an important niche for long-term intracellular fungal survival and replication.
Adrian Heckart, Jean-Christophe Cocuron, Stephanie C. Ray, Chad A. Rappleye, Ana P. Alonso   +4 more
doaj   +1 more source