Invasive fungal infections (IFIs) are a leading cause of morbidity and mortality in children with hematological malignancies as well as those undergoing hematopoietic stem cell transplantation (HSCT). Extreme immunological dysregulation secondary to severe neutropenia, T‐cell lymphopenia, graft‐versus‐host disease (GVHD), intensive chemotherapy ...
Matin Pourghasem +11 more
wiley +1 more source
Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding [PDF]
Fep1, the iron-responsive GATA factor from the methylotrophic yeast Pichia pastoris, has been characterised both in vivo and in vitro. This protein has two Cys(2)-Cys(2) type zinc fingers and a set of four conserved cysteines arranged in a Cys-X-5-Cys-X ...
Battistoni, Andrea +8 more
core +4 more sources
Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade +4 more
wiley +1 more source
Recent studies have shown that some drugs that are not routinely used to treat fungal infections have antifungal activity, such as protease inhibitor antiretroviral drugs. This study investigated the in vitro susceptibility of Histoplasma capsulatum var.
Raimunda Sâmia Nogueira Brilhante +12 more
doaj +1 more source
ABSTRACT Extracellular vesicles produced by pathogenic organisms play a role in host recognition and invasion across kingdoms, including fungi interacting with their plant hosts. Little is known about EVs from phytopathogenic fungi compared to human fungal pathogens.
Matin Ghaheri +7 more
wiley +1 more source
Non-resolving pneumonia: A rare presentation of progressive disseminated histoplasmosis
Histoplasmosis, a fungal disease caused by Histoplasma capsulatum, is endemic in North and South America. Except few scattered cases, the disease is considered to be a non-entity in India.
Supriya Sarkar +3 more
doaj +1 more source
Localized Histoplasma capsulatum osteomyelitis of the fibula in an immunocompetent teenage boy: a case report [PDF]
BACKGROUND: Infection of local bone with Histoplasma capsulatum is rare and difficult to diagnosis, and occurs particularly in immunocompetent subjects, who are more likely to be affected by a wide range of organisms.
Lu Huang, Xudong Miao, Yongping Wu
core +1 more source
Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant‐Associated Infection Surveillance Network ( TRANSNET ) [PDF]
Background Invasive fungal infections are a major cause of morbidity and mortality among solid organ transplant ( SOT ) and hematopoietic cell transplant ( HCT ) recipients, but few data have been reported on the epidemiology of endemic fungal ...
Alexander, B.D. +18 more
core +1 more source
A survey to determine the occurrence of Histoplasma capsulatum and Cryptococcus neoformons in air-conditioners [PDF]
Call number: LD2668 .T4 1968 B68Master of ...
Botard, Robert William.
core
Tonsillar ulceration as manifestation of disseminated African histoplasmosis in an immunocompetent Portuguese host [PDF]
Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466580/Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. Rare in Europe but endemic in some regions of Brazil, United States, Africa and Asia.
Cardoso, L. +3 more
core +3 more sources

