Atypical disseminated cutaneous histoplasmosis in an immunocompetent child, caused by an "aberrant" variant of Histoplasma capsulatum var. capsulatum [PDF]
A case of atypical disseminated cutaneous histoplasmosis in a five-year old, otherwise healthy child, native and resident in São Paulo metropolitan area is reported. Cutaneous lesions were clinically atypical.
LACAZ Carlos da Silva +9 more
doaj +4 more sources
Synthesis and antifungal activity in vitro of isoniazid derivatives against histoplasma capsulatum var. capsulatum. [PDF]
ABSTRACT Histoplasmosis is a severe infection that affects millions of patients worldwide and is endemic in the Americas. Amphotericin B (AMB) and itraconazole are highly effective for the treatment of severe and milder forms of the disease, but AMB is toxic, and the bioavailability of itraconazole is erratic.
de Aguiar Cordeiro R +11 more
europepmc +4 more sources
Synergistic effect of antituberculosis drugs and azoles in vitro against Histoplasma capsulatum var. capsulatum. [PDF]
ABSTRACT This study evaluated in vitro interactions of antituberculosis drugs and triazoles against Histoplasma capsulatum . Nine drug combinations, each including an antituberculosis drug (isoniazid, pyrazinamide, or ethambutol) plus a triazole (itraconazole, fluconazole, or ...
Cordeiro Rde A +14 more
europepmc +4 more sources
A complementary tool for management of disseminated Histoplasma capsulatum var. capsulatum infections in AIDS patients [PDF]
In South America, disseminated histoplasmosis due to Histoplasma capsulatum var. capsulatum (H. capsulatum), is a severe and frequent opportunistic infection in AIDS patients. In areas outside the USA where specific-Histoplasma antigen detection is not available, the diagnosis is difficult. With the galactomannan antigen (GM) detection, a test commonly
Xavier, Iriart +15 more
openaire +4 more sources
An aberrant variant of Histoplasma capsulatum var. capsulatum [PDF]
We studied an aberrant culture of Histoplasma capsulatum var. capsulatum isolated from synovial fluid collected from the right elbow of a patient from Kansas. Colonies on Sabouraud glucose agar and other routine mycological media were glabrous to soft, moist, heaped, deeply folded or convoluted, and orange-brown with a white, irregular margin ...
D A, Sutton +3 more
openaire +2 more sources
Introduction Histoplasmosis is a fungal disease caused by Histoplasma capsulatum. Histoplasma capsulatum var capsulatum is found in Martinique. Cluster cases following working in deserted house, have been described in Martinique. Cases of acute pulmonary
Moustapha Agossou +4 more
doaj +1 more source
An unneutered female cat of unknown age presented bloody lesions on the edematous face, and respiratory signs. Cytology and culture from the skin sample collected with fine-needle aspiration showed yeasts inside activated macrophages, and fungal growth ...
Liliane Lima da Silva Lomônaco +12 more
doaj +1 more source
Phenotypic characterization of Histoplasma capsulatum var. capsulatum isolates and antigenic standardization for histoplasmosis diagnosis [PDF]
Roseli Santos de Freitas
doaj +4 more sources
Molecular Detection of Histoplasma capsulatum var. capsulatum in Human Clinical Samples [PDF]
ABSTRACT We developed a seminested PCR for the diagnosis of histoplasmosis that amplifies a portion of the Histoplasma capsulatum H antigen gene. This assay is highly sensitive and specific, being able to detect genomic material corresponding to less than 10 yeast cells without cross-reaction against other
Andrea, Bracca +5 more
openaire +2 more sources
A murine monoclonal antibody exhibiting high species specificity for Histoplasma capsulatum var. capsulatum [PDF]
A monoclonal antibody (mAb) exhibiting a high degree of species specificity for the yeast phase of the dimorphic fungus Histoplasma capsulatum was produced by a modification of the standard mAb production protocol. The technique for generating mAbs involved the use of the immunosuppressive drug cyclophosphamide to diminish the response in mice to ...
A J, Hamilton +4 more
openaire +2 more sources

