Results 41 to 50 of about 1,368,556 (344)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Archaeology and the Natural Environment. Foreword

open access: yesInternet Archaeology, 2023
How we manage our land, water and ecosystems in an integrated way is profoundly affecting our approaches to archaeology. A foreword to issue 62.
Barney Sloane
doaj   +1 more source

Historic Preservation Law: The Metes & Bounds of a New Field [PDF]

open access: yes, 1981
Historic Preservation Law has come to mean that combination of regulations, common-law property principles, tax incentives, and adjective law in administrative proceedings, governing historic sites and property within the United States. Although Congress
Robinson, Nicholas A.
core   +1 more source

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

The Baptist Church in Warren: Rehabilitation and Preservation Report [PDF]

open access: yes, 2013
The Baptist Church in Warren is located in the Warren Waterfront Historic National Register District. Warren also has a Voluntary Historic District. Both the National Register Nomination and the Voluntary Historic District have regulations which pertain ...
Bambara, Lauren   +4 more
core   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Simulation of emissions from pottery kilns in the Roman period

open access: yesMeteorological Applications
Present‐day air quality is known through dense monitoring and extensive pollution control mechanisms. In contrast, knowledge of historical pollution, particularly before the industrial revolution, is accessible only through occasional reports of singular
Clemens Drüe
doaj   +1 more source

Post-Theory and Beyond

open access: yesRevista Brasileira de Literatura Comparada, 2021
This article surveys and assesses the eclectic trends in literary theory and criticism in the posttheory age with a focus on three rubrics: the cultural turn, the historic turn, and the affective turn.
Luiz Fernando Valente
doaj  

Challenges Facing the State Management of Historic Shipwrecks in English Territorial Waters

open access: yesInternet Archaeology, 2020
Funding challenges for maritime archaeology in the UK means that Historic England has to seek creative solutions to historic wreck management. This article details how historic shipwrecks in English territorial waters are protected, managed and conserved
Hefin Meara
doaj   +1 more source

Public Benefit as Community Wellbeing in Archaeology

open access: yesInternet Archaeology, 2021
This article outlines the theory and strategy behind Historic England's (HE) Wellbeing Strategy. It acknowledges the relevance of wellbeing to HE's core purpose, and proposes ways in which wellbeing can be built into archaeological and heritage projects.
Linda Monckton
doaj   +1 more source

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