Results 241 to 250 of about 482,315 (310)

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Determining Access for a City-Wide Extracorporeal Cardiopulmonary Resuscitation (ECPR) Initiative Using Geospatial Analysis. [PDF]

open access: yesAcad Emerg Med
Prucnal CK   +9 more
europepmc   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

open access: yesAdvanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim   +12 more
wiley   +1 more source

Underlying brain and genetic mechanisms linking historic phone use patterns, visual decline, and dementia risk in middle-aged and older adults. [PDF]

open access: yesAlzheimers Dement (Amst)
Zhang X   +13 more
europepmc   +1 more source

Patterns and Drivers of Pest and Disease Occurrence in UK Treescapes. [PDF]

open access: yesGlob Chang Biol
Stewart PS   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy