Results 241 to 250 of about 218,779 (308)

Unlocking natural history collections to improve eDNA reference databases and biodiversity monitoring. [PDF]

Bioscience
Schmid S, Straube N, Albouy C, Delling B, Maclaine J, Matschiner M, Møller PR, Nocita A, Palandačić A, Rüber L, Sonnewald M, Alvarez N, Manel S, Pellissier L.   +13 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

New Perspectives on European Wildcat (<i>Felis silvestris</i>, Schreber 1777) Habitat Suitability in Britain: Integrating Fossil Records to Improve Baselines for Reintroduction. [PDF]

Ecol Evol
Mills M, Hemmingham L, Schreve D.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Scaling up orphan crop research: genebank genetics highlight geographic structure in cultivated cowpea from 10 617 global accessions. [PDF]

Plant J
Pearson S, Hathorn A, Sun S, Cruickshank A, Shatte T, Munisse P, Wairimu MM, Conner J, Koltunow A, Vielle-Calzada JP, Ozias-Akins P, Ishii T, Dell'Acqua M, Norton S, Tao Y, Jordan D, Mace E.   +16 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Back to the future: Using herbarium specimens to isolate nodule-associated bacteria. [PDF]

Ecol Evol
Petipas RH, Antoch AA, Eaker AA, Kehlet-Delgado H, Friesen ML.   +4 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

A database of geomagnetic observatory monthly means: from historic to the satellite era. [PDF]

Earth Planets Space
Brown W, Macmillan S, Maume E, Eaton E.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source