Results 111 to 120 of about 1,116,516 (283)

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Other title: Shared stewardship 2018-2023; Other title: State historic preservation plan

, 2018
Previously issued as: Investment in Connecticut--state historic preservation plan 2011-2016 / prepared for the State Historic Preservation Office, Department of Economic and Community Development, State of Connecticut, Dannel P.

core   +1 more source

Making – or Picking – Winners: Evidence of Internal and External Price Effects in Historic Preservation Policies [PDF]

Much has been written identifying property price effects of historic preservation policies. Little attention has been paid to the possible policy endogeneity in hedonic price models.
Krupka, Douglas J., Noonan, Douglas S.
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Historic preservation news and notes [PDF]

, 2019
The State Historic Preservation Office at the South Carolina Department of Archives and History publishes a monthly newsletter featuring agency programs and events, and highlights those of state and national preservation groups.
South Carolina State Historic Preservation Office
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

From Memory to Reality: Preserving and Transmitting Collective Memory in Urban Historic Neighborhoods

SAGE Open
Historic neighborhoods are crucial repositories of a city’s cultural heritage. However, during urban renewal and development, the emphasis often falls on physical preservation and renovation, leading to the neglect of the “collective memory” inherent in ...
Yuting Dai, Jingru Zhang, Jie Zhang, Wan Ahmad Jaafar Wan Yahaya   +3 more
doaj   +1 more source

Scenic and historic America.

, 1917
Mode of access: Internet."Official bulletin of the American Scenic and Historic Preservation Society."This publication lasted for one issue only. Another serial with the same title and issued by the Society was published beginning in 1929.
American Scenic and Historic Preservation Society.
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