Results 41 to 50 of about 12,148 (290)

The Profitability Analysis Of Enhancement Of Parameters Of The Thermal Insulation Of Building Partitions

open access: yesArchives of Civil Engineering, 2014
The energy saving tendencies, in reference to residential buildings, can be recently seen in Europe and in the world. Therefore, there are a lot of studies being conducted aiming to find technical solutions in order to improve the energy efficiency of ...
Życzyńska A., Cholewa T.
doaj   +1 more source

Conservation Challenges and Emerging Trends of Digital Preservation for UNESCO Architectural Heritage, Pakistan

open access: yesConservation, 2021
Recent worldwide initiatives at world heritage forums, especially UNESCO, have increased the importance of architectural heritage. Architectural heritage includes built structures that are of outstanding value of natural and cultural identity and require
Asma Khalid
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

URZĄD KONSERWATORSKI A ZABYTEK, CZYLI O WPŁYWIE URZĘDU NA PRZYGOTOWANIE I REALIZACJĘ PRAC KONSERWATORSKICH

open access: yesOchrona Dziedzictwa Kulturowego, 2016
Under the Act of 23 July, 2003 on the Protection and Guardianship of Monuments, employees of historic preservation offices supervise works carried out to historic monuments and sites as well as determine their scope.
Małgorzata Korpała
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

WAWEL W POLSKIM SYSTEMIE SŁUŻB KONSERWATORSKICH

open access: yesOchrona Dziedzictwa Kulturowego, 2016
The article describes the system of historic preservation care provided to the architectural complex of outstanding historical value located on the Wawel Hill.
Piotr M. Stępień
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Anno 1928 competition for projects of Orthodox Churches in the Second Polish Republic: in searching new architectural identity

open access: yesBudownictwo i Architektura, 2013
Staying of Polish lands in the Russian Empire was accompanied by active construction of Orthodox churches in “Moscow-Byzantine” style. After regeneration of II Rzeczpospolita its authorities try to generate such new trends in church architecture, which ...
Petro Rychkov, Olga Mykhaylyshyn
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy