Results 71 to 80 of about 8,305,004 (258)

The Psychological Content of Relationship between Sense and Meaning in Cultural-Historical Approach

open access: yesКультурно-историческая психология, 2018
The paper considers L.S. Vygotsky’s cultural-historical theory and its interpretation in modern psychology. It shows that psychological content of many concepts introduced by L.S. Vygotsky differs greatly from that of the ones used in theory and practice
Kravtsova E.E., , Kravtsov G.G.,
doaj   +1 more source

Principles and practices of methodology and methods in cross-cultural psychology

open access: yes, 2022
Principles of methodology in (cross-)cultural psychology are discussed and how these work out in practice. We propose that the frequently mentioned contrasts between context-specificity and universality of psychological functioning, and between ...
Poortinga, Ype H.   +1 more
core  

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Lecture Four. Structure and Functions of Cultural Operations in Children

open access: yesКультурно-историческая психология, 2021
Vygotsky L.S.
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Positive psychology and ideas of cultural-historical school of L.S. Vygotsky

open access: yesКультурно-историческая психология, 2017
In the article was carried out a comparative analysis between two distinctive psychology schools: the cultural-historical psychology of L.V. Vygotsky and the positive psychological school.
Vasilev V.K.,, Stamatov R.I.,
doaj   +1 more source

Developing the Ideas of the Scientific School of L.S. Vygotsky: Scientific Publications of the Journal “Cultural-Historical Psychology” (2005—2016)

open access: yesКультурно-историческая психология, 2016
The article presents the analysis of the development of the ideas of L.S. Vygotsky’s school using the example of the publications in the international scientific journal “Cultural-Historical Psychology” (for the period 2005 through 2016). Over the period
Shvedovskaya A.A.,
doaj   +1 more source

The Children’s Playground in the Context of Cultural-Historical Psychology

open access: yes, 2016
The article describes the possible application of the principles of cultural-historical approach and activity theory to the inspection of toys and play environments.
Smirnova E.O.,   +3 more
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

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