Results 51 to 60 of about 2,388,004 (329)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Political borders in Polish territory according to the Soviet atlas of 1940

Polish Cartographical Review, 2019
The author presents Karmannyj Atlas Mira (Pocket Atlas of the World) which was published in Leningrad in 1940. It shows political borders existing in Polish territory at that time. Those borders resulted from the Soviet-German agreement reached in August
Eberhardt Piotr
doaj   +1 more source

Contemporary atlases of Serbia [PDF]

Zbornik Radova: Geografski institut "Jovan Cvijić", 2011
There are a number of publications under the title ‘Atlas of Serbia’, but few of them are real atlases, i.e. cartographic works in the traditional sense of the word.
Vemić Mirčeta, Lović Suzana
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Data release: Digitized Dialect Atlas of Finnish by Lauri Kettunen

Digital Humanities in the Nordic and Baltic Countries Publications
In this paper, we present a new digitized version of the Dialect Atlas of Finnish and offer the data as open access. The Atlas was compiled in the early 1920s and 1930s to document the variation of Finnish language.
Jenni Santaharju, Kaj Syrjänen, Terhi Honkola, Perttu Seppä, Outi Vesakoski, Unni Leino   +5 more
doaj   +1 more source

Ein amharischer Atlas aus Malta

Aethiopica, 2011
In August 2008 Professor Dr. Hans H. Kaminsky of the Institute of History of the University of Giessen, gave me an Amharic atlas, printed in Malta, which he had bought several years ago, at the Giessen flee-market.
Ewald Wagner
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

SCIENTIFIC АND METHODICAL SUPPORT OF THE ARCTIC NATIONAL ATLAS

InterCarto. InterGIS, 2017
In recent years many maps, atlases and other cartographic products have been out in Russia and other countries. They reflect natural conditions and socio-economic processes in the Arctic region.
S. A. Dobrolyubov, N. S. Kasimov, V. S. Tikunov, N. I. Tulskaya   +3 more
doaj   +1 more source