Results 121 to 130 of about 248,895 (305)

Impact of Architectural Styles on Acoustic Characteristics in Selected European Churches

open access: yesArchitecture
This study explores the acoustic properties of European Churches, influenced by architectural design, historical context, and spatial configurations. A comparative analysis of 83 Churches from different regions and periods combines literature reviews and
Samantha Di Loreto   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The Effects of Urban Pollution on the “Gesù Nuovo” Façade (Naples, Italy): A Diagnostic Overview

open access: yesAtmosphere
The deterioration of stone heritage in urban environments is mainly the product of sources of air pollution like vehicular traffic and domestic heating.
Alessandro De Rosa   +6 more
doaj   +1 more source

The Kentennial, Newsletter of the Kent Historical Society, Volume 57, Spring 2006

open access: yes, 2006
The Centennlall Kent Historical Society Newsletter Spring 2006 234 South Water Street, Kent University School trophies, Edison record player, vintage medical tools among Museum's new exhibits Director's Report by Guy Pernetti Now that Kent is celebrating

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ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

[Texas Historical Commission Marker: Hall Furniture Building]

open access: yes, 2011
Photograph of the Texas Historical Commission marker for Hall Furniture Building in Sherman, Texas. Text: Former Missourian and Civil War veteran Rufus Gaines Hall established a Sherman Dry Goods Store in 1868.
West, Carolyn Effie
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Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Non-Destructive Testing of a Historical Vault Using Ground Penetrating Radar Method

open access: yesCivil and Environmental Engineering
The article presents the results of research conducted in the Main Building of the Gdańsk University of Technology, which was destroyed in the World War II, reconstructed and included in the Register of Historic Buildings several decades ago.
Ciborowski Tomasz   +2 more
doaj   +1 more source

Surveying of historical monuments affected by mining operations

open access: yesТехнічна інженерія
In Kryvyi Rih, the area of land currently occupied by mining operations and previously disturbed by mining operations continues to expand, resulting in the destruction of valuable fertile soils and the absorption of buildings and structures located on ...
O.V. Dolgikh   +3 more
doaj   +1 more source

Comparison between dynamic simulations and real energy consumptions of historical buildings

open access: yes, 2015
The retrofitting challenge for historical buildings consists of finding solutions that improve energy efficiency, preserving at the same time the buildings’ cultural and historical value.
BIANCHI, FRANCESCO   +2 more
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