Results 41 to 50 of about 248,895 (305)

Use of Unmanned Aerial Vehicle Technology in the Protection of Goods of Cultural Interest (GCIs): The Case of the Castle of Cala (Huelva, Spain)

Architecture
Currently, the use of modern technologies, such as UAVs, allows for a detailed analysis of the protection of Sites of Cultural Interest (BICs) in Spain.
Gina M. Núñez-Camarena, Rafael Herrera-Limones, Álvaro López-Escamilla   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Historical and cultural value of the yard wing of a revenue house in the historical center of Saint Petersburg

Архитектура, строительство, транспорт
The basis of the work is the results of the historical and cultural research of inner-block buildings, including residential multistorey ones in Saint Petersburg. The author studied the history of the inner-block building at 23b Egorova Street, letter A,
O. O. Chainikova
doaj   +1 more source

Occupants’ perception of historical buildings’ indoor environment. Two case studies

, 2018
In Europe, some historical cities have more than 50% of buildings dated from before 1920. Nowadays, these buildings faces challenges when adapted to the current necessities of livability, environmental and economical sustainability.
V. Fabi, Corgnati, Stefano Paolo, Giorgia Spigliantini, G. Spigliantini, M. Schweiker, Fabi, Valentina, Stefano Paolo Corgnati, Valentina Fabi, Spigliantini, Giorgia, Schweiker, Marcel, S. P. Corgnati, Marcel Schweiker   +11 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Effect of Solar Control Films on Enhancing the Energy Efficiency of Historic Buildings

Energies
The use of solar control foils (SCFs) is a minimally invasive method that enables energy savings while preserving the original character of historic building facades.
Miroslaw Zukowski, Giovanni Semprini, Krzysztof Rajski   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Faktor-Faktor Keterbengkalaian Benteng Toboali Sebagai Bangunan Bersejarah

Jurnal Pembangunan Wilayah dan Kota, 2014
Buildings and areas that have historical significance should essentially be seen as an object of cultural heritage that needs to be protected and preserved.
Ari Sutanto
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source