Results 181 to 190 of about 6,086,370 (315)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Contributions to the Historical Society of Montana

The Mississippi Valley Historical Review, 1918
openaire   +3 more sources

Autism in Criminal-Justice and Forensic Settings: A Systematic Review and Meta-Analysis with an Exploratory Bidirectional Synthesis. [PDF]

Behav Sci (Basel)
Rusu RV, Delcea C.
europepmc   +1 more source

The Southwestern Historical Quarterly, Volume 56, Number 4, April 1953

, 1953
The Texas State Historical Association Quarterly Report includes "Papers read at the meetings of the Association, and such other contributions as may be accepted by the Committee" (volume 1, number 1).
Texas State Historical Association, Carroll, H. Bailey   +1 more
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Southwestern Historical Quarterly, Volume 77, Number 4, April 1974

, 1973
The Texas State Historical Association Quarterly Report includes "Papers read at the meetings of the Association, and such other contributions as may be accepted by the Committee" (volume 1, number 1).
Texas State Historical Association, Frantz, Joe B.   +1 more
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Global Burden and Future Projections of Alopecia Areata: A Global Burden of Disease Study 2023 Analysis. [PDF]

J Clin Med
Gupta AK, Pellegrino G.
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Permeability Is the Key in Sublingual and Buccal Drug Delivery. [PDF]

Pharmaceutics
Alfawaz RMO, Almoazen H.
europepmc   +1 more source