Results 61 to 70 of about 1,807,520 (288)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
HISTORICAL COST AND FAIR VALUE WITHIN THE CONTEXT OF FINANCIAL CRISIS [PDF]
Challenges of the Knowledge Society, 2011 Financial crisis determined the fast extension of global financial bankruptcy upon the world, representing at the same time the first crisis of the accounting term of "fair value", under the shade of which subsists a number of standards which request to ...
DIANA ELENA BRINZA
doaj
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
THE INFLUENCE OF ACCOUNTING POLICIES OVER THE ENTITIES’ RESULT [PDF]
Annals of the University of Petrosani: Economics, 2013 This article started from the idea that International Accounting and Financial Reporting Standards have had a major impact over the accounting world.
ALICE EMILIA ŢINTA
doaj
On the relationship between hurricane cost and the integrated wind profile [PDF]
, 2016 It is challenging to identify metrics that best capture hurricane destructive potential and costs. Although it has been found that the sea surface temperature and vertical wind shear can both make considerable changes to the hurricane destructive ...
Toumi, R, Wang, S
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Inflation adjustments of financial statements: Implication to price index and performance
International Journal of Academe and Industry ResearchThis paper examines the critical role of inflation accounting in adjusting financial statements to accurately reflect the impact of inflation on the economy.
Kawa Wali +2 more
doaj +1 more source
A Better Alternative to Piecewise Linear Time Series Segmentation [PDF]
, 2005 Time series are difficult to monitor, summarize and predict. Segmentation organizes time series into few intervals having uniform characteristics (flatness, linearity, modality, monotonicity and so on).
Lemire, Daniel
core +8 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source