Results 21 to 30 of about 131,188 (265)

Comparative assessment of machine learning models for daily streamflow prediction in a subtropical monsoon watershed

open access: yesScientific Reports
Accurate streamflow prediction is critical for flood warning and water resources management in subtropical monsoon watersheds, yet optimal model selection remains challenging. This study compared seven machine learning models, including Linear Regression
Zhi Zhang   +6 more
doaj   +1 more source

The long and winding road

open access: yesDocumenta Praehistorica
In this paper we address the biography of a set of copper nails recovered in 1998 from a Late Iron Age structure located at the archaeological site of Puig de Sa Morisca (Mallorca, Spain).
Laura Perelló Mateo   +4 more
doaj   +1 more source

Austrian teachers’ understanding and teaching of historical culture: challenges for the implementation of curriculum reforms in Austria

open access: yesHistory Education Research Journal, 2022
In Austria, there have been repeated reforms of history curricula in recent years. In particular, these reforms have had the goal of implementing competence orientation.
doaj   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Don Juan de Austria, un héroe del barroco temprano, en la cultura histórica del siglo xx

open access: yesLes Dossiers du GRIHL, 2012
This article presents the initial results of an on-going research project: a case-study of twentieth-century European popular historical culture. It focuses on the hero of the Battle of Lepanto, Don Juan of Austria (1547-1578). By using different sources,
Fernando Sánchez-Marcos
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Studying the War-Era Historical and Cultural Heritage Losses in the Hero City of Novorossiysk

open access: yesСибСкрипт
Novorossiysk is among the ten cities in European Russia that suffered the most from military action during the Great Patriotic War of 1941–1945. The authors analyzed the scale of wartime architectural loss in Novorossiysk by using materials from central ...
Vasily E. Alekseev, Pavel V. Prokhoda
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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