Results 41 to 50 of about 148,696 (299)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Environmental science applications with Rapid Integrated Mapping and analysis System (RIMS) [PDF]

open access: yes, 2016
The Rapid Integrated Mapping and analysis System (RIMS) has been developed at the University of New Hampshire as an online instrument for multidisciplinary data visualization, analysis and manipulation with a focus on hydrological applications.
Gordov, E.   +4 more
core   +2 more sources

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell   +3 more
wiley   +1 more source

Impact of Late Pleistocene-Holocene climatic fluctuations on the phylogeographic structure and historical demographics of Zamia prasina (Cycadales: Zamiaceae)

open access: yesBotan‪ical Sciences, 2019
Background: Glacial periods during the Pleistocene have been hypothesized to have greatly influenced geographical patterns of genetic structure and demography of many tropical species.
Grecia Montalvo-Fernández   +7 more
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Maori demography in Aotearoa New Zealand: Fifty Years on [PDF]

open access: yes, 2011
Writing in the Journal of the Polynesian Society fifty years ago, budding demographer Ian Pool asked: “When is a Maori a ‘Maori’”? His assertion that cultural self-identification was the only credible way to define Māori collectively in official ...
Kukutai, Tahu
core  

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou   +9 more
wiley   +1 more source

The Causes of Changes in Fertility in Northern Namibia

open access: yesFinnish Yearbook of Population Research, 2017
The main aim of this study was to analyse fertility change in Ovamboland (North-Central Namibia) (1927–2010) and the Kavango region (North-East Namibia) (1935–1979) in Northern Namibia.
Veijo Notkola   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Searching for demography's missing link: Momentum [PDF]

open access: yes, 2005
This paper is both more theoretical and highly applied; both methodological and policy-oriented. Empirically until recently there has been little work on momentum effects.
Pool, Ian
core  

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