Results 71 to 80 of about 148,696 (299)

Exploring the Variations of the Sex Ratio at Birth from an Historical Perspective

Statistica, 2015
Variations in sex ratios at birth is still an active research field and several studies in the last decades have focused on this topic. In this article, studies on the main determinant of long- and short-term trends are briefly reviewed, taking into ...
Francesco Scalone, Rosella Rettaroli
doaj   +1 more source

Mitochondrial DNA reveals genetic structuring of Pinna nobilis across the Mediterranean Sea [PDF]

, 2013
Pinna nobilis is the largest endemic Mediterranean marine bivalve. During past centuries, various human activities have promoted the regression of its populations.
Castelli, Alberto, Casu, Marco, Cossu, Piero, Cristo, Benedetto, Curini Galletti, Marco, Dedola, Gian Luca, Francalacci, Paolo, Franzoi, Piero, Lai, Tiziana, Maltagliati, Ferruccio, Sanna, Daria, Scarpa, Fabio   +11 more
core   +4 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Op de snijtafel van de genderhistoricus. Androcentrisme in de historische demografie

Tijdschrift voor Sociale en Economische Geschiedenis, 2020
This article presents a discussion and analysis of the way in which the concept of gender is applied as an analytical category in the field of historical demography.
Angélique Janssens
doaj   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Interdisciplinary Approach to Spationtemporal Population Dynamics. The North Orkney Population History Project

Historical Life Course Studies, 2019
The North Orkney Population History Project is a multidisciplinary data collection, digitization, and analysis effort that aims to reconstruct longitudinal demographic, environmental, and economic change. We describe the motivation, methodological
Julia A. Jennings, Corey S. Sparks, Timothy Murtha   +2 more
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Twenty-five key evolutionary insights from the phylogeographic revolution in population genetics [PDF]

, 2007
An overview is provided of 25 novel perspectives that the field of phylogeography has brought to scientific studies of population genetics and speciation.
Avise, JC
core  

Standardization and Control for Confounding in Observational Studies: A Historical Perspective

, 2014
Control for confounders in observational studies was generally handled through stratification and standardization until the 1960s. Standardization typically reweights the stratum-specific rates so that exposure categories become comparable.
Clayton, David, Keiding, Niels
core   +1 more source