Results 91 to 100 of about 371,423 (306)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Do Effortful Apologies Matter in International Historical Disputes? Experimental Evidence from South Korea

open access: yesJournal of East Asian Studies
Political apologies have become an important tool for addressing historical injustices, yet their effectiveness—especially in international contexts—remains debated.
Jaeseok Yang
doaj   +1 more source

The role of women in disputing among the Ila of Zambia: political adaptation in legal change [PDF]

open access: yes, 1981
African Studies Center Working Paper No. 46This article examines the role of female litigants within the changing social context of disputing and dispute processing among the Ila of Zambia.
Cutshall, Charles S.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

SENKAKU ISLANDS DISPUTE BETWEEN JAPAN AND CHINA FROM THE END OF THE COLD WAR UNTIL NOW—IMPACT ON THE SITUATION POLITICS IN THE ASIA-PACIFIC REGION [PDF]

open access: yesRomanian Journal of Historical Studies
The article aims to explain the fundamental sovereignty dispute over the Senkaku (Diaoyu) Islands between China and Japan by employing key historical research methodologies, including both historical and logical approaches.
Nguyen Khoa Tuan
doaj  

Disputed paternity: the historical perspectives.

open access: yesAnnals of the Academy of Medicine, Singapore, 1993
Requests for blood tests to resolve issues of disputed paternity fall under three main categories: (1) Proof of adultery; (2) Proof of kinship (a) in claims for citizenship, (b) to make material changes to the Birth Certificate, (c) for settlement of family disputes usually in inheritance matters; and (3) Investigation of sex crimes like rape and ...
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

The Implications of Land Use Dynamics on Land Disputes in Depok City, West Java

open access: yesBHUMI: Jurnal Agraria dan Pertanahan
: Land use dynamics represent an inevitable phenomenon in the process of urban development. The large-scale conversion of land in Depok City, West Java, has triggered various issues, particularly concerning land tenure, land use practices, and the ...
Ella Whidayanti
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Environmental Water Markets: Restoring Streams Through Trade [PDF]

open access: yes, 2010
This Policy Series explores the evolving institutional settings in western states1 for restoring and preserving instream flows. The focus is on how markets can provide an efficient and equitable solution for allocating water among increasingly ...
Brandon Scarborough
core  

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