Results 101 to 110 of about 834,485 (300)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Automatic Vectorization of Historical Maps

open access: yesGEOmedia
For the most diverse practical purposes and communication needs (from trade to conquests or exploratory voyages), man has always represented space through the production of maps.
Elisa Farella   +2 more
doaj  

Utilizing historical maps in identification of long-term land use and land cover changes. [PDF]

open access: yesAmbio, 2023
Mäyrä J   +4 more
europepmc   +1 more source

[Review of] Neshnabek: The People [PDF]

open access: yes, 1982
The Potawatomi Indians (Prairie Band) of Kansas are portrayed in this film which has been some forty to fifty years in the making. The original footage was taken by Floyd A. Schultz, an amateur anthropologist, between 1930 and 1941.
Gradwohl, David M.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Beach Erosion in the Gulf of Castellammare di Stabia in Response to the Trapping of Longshore Drifting Sediments of the Gulf of Napoli (Southern Italy)

open access: yesGeosciences, 2018
The results of this study have allowed verification that longshore sediment transport along the coast of Napoli Gulf (southern Italy) takes place from Northwest to Southeast.
Micla Pennetta
doaj   +1 more source

Curriculum learning-based strategy for low-density archaeological mound detection from historical maps in India and Pakistan. [PDF]

open access: yesSci Rep, 2023
Berganzo-Besga I   +11 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Towards the automated large-scale reconstruction of past road networks from historical maps. [PDF]

open access: yesComput Environ Urban Syst, 2022
Uhl JH, Leyk S, Chiang YY, Knoblock CA.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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