Results 151 to 160 of about 4,978,738 (338)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Review of the methods of cartographic presentation of warfare

Polish Cartographical Review, 2015
Maps, depicting the warfare, are elaborated according to the rules developed over the years. Although, they are not free of errors. The authors draw our attention to the diversity of methods related to the cartographic presentations, which are shown on ...
Augustyniak Jacek, Kuźma Marta, Pędzich Paweł   +2 more
doaj   +1 more source

Hydrological summary for the United Kingdom: June 2013 [PDF]

, 2013
The monthly summary of hydrological conditions in the United Kingdom is compiled as part of the National Hydrological Monitoring Programme (a joint CEH and BGS enterprise).
Clemas, Sandie, Lewis, Melinda, Parry, Simon   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Hydrological summary for the United Kingdom: January 2012 [PDF]

, 2012
The monthly summary of hydrological conditions in the United Kingdom is compiled as part of the National Hydrological Monitoring Programme (a joint CEH and BGS enterprise).
Marsh, Terry, Parry, Simon, Sanderson, Felicity   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Between scientific rigor and perceptive component. Representing the landscape of the “royal salt works” of Cagliari in the 19th century (Sardinia, Italy)

Disegnare con, 2019
The case study is part of a research that analyzes the potentiality of historical maps as a tool to support the knowledge and protection of the landscape.
Andrea Pirinu
doaj  

Working digitally with historical maps [PDF]

, 2013
Southall, Humphrey
core   +1 more source

Hydrological Summary for the UK: July 2010 [PDF]

, 2010
The monthly summary of hydrological conditions in the United Kingdom is compiled as part of the National Hydrological Monitoring Programme (a joint CEH and BGS enterprise).
Marsh, Terry, Sanderson, Felicity
core  

Mapping Historical Consciousness

Journal of Autonomy and Security Studies, 2017
The article investigates the temporal and spatial structure of historical consciousness among secondary school students from ten locations around the Baltic and Mediterranean seas. It examines what eras and spaces in history that are important to the students, and discusses how the mental maps of individuals at a certain location are affected by ...
openaire   +1 more source