Results 31 to 40 of about 79,666 (263)
RHS Revista Humanismo y Sociedad, 2020 The aim of this paper is to provide a review of the concept of historical memory, how it arose and developed historically since World War II, as well as to highlight the shift caused by the concept of memory in the field of historiography and in the ...
Fray Esteban Atehortúa-Aguirre
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
BETWEEN AMNESIA AND THE «WAR OF MEMORIES»: POLITICS OF MEMORY IN THE MUSEUM NARRATIVES OF UKRAINE [PDF]
Muzeológia a Kultúrne Dedičstvo, 2019 This paper seeks to lay out certain critical reflections on social transformations, changes in memory politics and its representation in the Ukrainian museum narratives over the years of independence.
Verbytska Polina, Kuzmyn Roman
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Technologies for Transforming the historical memory of the Great Patriotic War in Post-Soviet Russia
Дискурс Пи, 2020 Based on the analysis of the content of films released during Perestroika and in postSoviet Russia, the article describes the main technologies for transforming the historical memory of the Great Patriotic war.
Kokoulin V.G.
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Clio y Asociados, 2020 This article aims to put in tension three types of historical narratives referring to the recent history of Chile. Based on the autobiographical notes of a Chilean writer, it analyzes the narrative of the generation that lived and ...
Fabián González Calderón
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Discourses of Historical Memory (Continuation)
Дискурс Пи, 2017 In the continuation of the article subject to review will be the methods and means by which social institutions perform the work on deciphering structures of identity of people from other historical periods, which can be applied for the analysis of our ...
K.S. Romanova
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