Results 41 to 50 of about 62,690 (298)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
MORPHOLOGICAL ANALYSIS OF HISTORICAL LANGUAGES [PDF]
Bulletin of the Institute of Classical Studies, 2016 Abstract This paper describes the design of a system for parsing ancient Greek morphologically, taking into account the distinctive requirements of studying a historical language. Sets of stems and inflectional patterns identified by URNs are expressed in a specified orthography, and are loaded dynamically when the parser is built ...
openaire +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Baltistica, 2017 The closest relatives of Balto-Slavic are Albanian and Indo-Iranian. Together with Armenian and Thracian, these are the satǝm languages, which together with Greek and Phrygian constitute the eastern part of Classic Indo-European.The obvious common ...
Frederik Kortlandt
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
An Optimality Theory Account of the Non-concatenative Morphology of the Nominal System of Libyan Arabic, with Special Reference to the Broken Plural [PDF]
, 2012 This work presents a full and unified investigation of the phenomenon of non-concatenative nominal morphology in Libyan Arabic (LA), with special reference to the formation of the broken plural (BP). The analysis provides a morphophonological account of
GABER, GABER,MEFTAH
core
, 2001 ForewordHyvät Ystävät, Hyvät Naiset ja HerratNow, as we have reached the time to initiate the 11th International Symposium on Dental Morphology, I am most happy to have you here in Oulu, Finland and I hope that you will enjoy every minute, every aspect ...
Mayhall, J. T. (John T.) +1 more
core +1 more source
Вестник Северного (Арктического) федерального университета: Серия «Гуманитарные и социальные науки»This article aimed to study the morphological and derivational composition of nouns and determine the ratio of their inflectional classes, as well as identify the most productive types of word formation and their stylistic correlation in the 1741 written
Nikolay V. Chugaev
doaj +1 more source
Frontiers in Endocrinology, 2023 BackgroundDisordered and hypomineralized woven bone formation by dysfunctional mesenchymal stromal cells (MSCs) characterize delayed fracture healing and endocrine –metabolic bone disorders like fibrous dysplasia and Paget disease of bone.
Giusy Di Conza +13 more
doaj +1 more source