Results 181 to 190 of about 220,864 (310)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Warwerri: A historical fantasy novel

This dissertation investigates historical trauma, cultural identity, and anti-colonial resistance through Warwerri, a historical fantasy novel centered on three generations of Igbo women during the Aba Women’s War of 1929.
Ossai, Ogochukwu B.
core  

Two hundred years of historical spawning and nursery data for coregonine fishes in the Laurentian Great Lakes. [PDF]

Sci Data
Brant CO, Silvis S, Bennion DH, Castiglione C, Tyrrell K, Hannahs K, Slattery M, Bunnell D, Honsey A, Tingley R, King K, Alofs KM, Ackiss A, Bronte CR, Smith J, Herbert M.   +15 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

The emergence and spread of a novel sequence type of Corynebacterium diphtheriae in Vietnam. [PDF]

Sci Rep
Hoang LH, Hoa LM, Hai PT, Ngoc DB, Thang NT, Ly PT, Nguyen PTL, Lan PT, Duong TN, Huong NTT, Morita M, Ha HTT, Senoh M.   +12 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

The Cambridge Introduction to the Eighteenth-Century Novel

A clearly written account of the development of the novel over the course of the long eighteenth century.Cover -- The Cambridge Introduction to the Eighteenth-Century Novel -- Title -- Copyright -- Dedication -- Contents -- Introduction -- Part I ...
London, April.
core  

From Zenana to courtroom: the politics of genre and gender in Sujata Massey's historical crime fiction. [PDF]

Front Sociol
G T N, Mukherjee A.
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

<i>OrgaCast</i>: A Trustworthy Spatiotemporal Diffusion Model for Fluorescence Organoid Forecasting. [PDF]

Proc AAAI Conf Artif Intell
Gao D, Gomez AH, Li M, El-Mokahal M, Yang H, Feng Y.   +5 more
europepmc   +1 more source