Results 231 to 240 of about 1,186,802 (304)

Automated image inpainting for historical artifact restoration using hybridisation of transfer learning with deep generative models. [PDF]

Sci Rep
Swathi B, Rao DBJ.
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

A bayesian dynamic borrowing framework for improving the efficiency of clinical trials. [PDF]

BMC Med Res Methodol
Zheng Z, Chen K, Zhu P, Wu H, Jiang S, Zhang D, Chow SC, Wu Y.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Dual-Criterion Approach Incorporating Historical Information to Seek Accelerated Approval With Application in Time-to-Event Group Sequential Trials. [PDF]

Stat Med
Ratta M, Saint-Hilary G, Barboux V, Gasparini M, Skanji D, Mozgunov P.   +5 more
europepmc   +1 more source

Emerging changes in lake temperature extremes and variability in South America. [PDF]

Clim Change
Dinh DA, Tong Y, Feng L, Fleischmann A, Jennings E, McCarthy V, Jordan S, Woolway RI.   +7 more
europepmc   +1 more source

A century of emergence: trends and patterns in human viral pathogens, 1900-2024, a systematic review. [PDF]

BMC Infect Dis
Quigley A, Chen R, Notaras A, Muluneh AG, Lim S, Chughtai AA, MacIntyre CR.   +6 more
europepmc   +1 more source

Maternal lineage diversity and health-related haplogroups in the Gilgiti and Kohistani populations of northern Pakistan. [PDF]

BMC Genomics
Adnan A, Rakha A, Tao L, Shen Q, Chen HD, He HF, Ullah MF, Nazir S, Zafar AA, Wang CC, Wang H.   +10 more
europepmc   +1 more source

Temporal stability and spatial patterns of genetic diversity in populations of the climate-vulnerable fucoid Scytothalia dorycarpa. [PDF]

J Phycol
Edgeloe JM, Coleman MA, Wood GV, Starko S, Nimbs MJ, Batley J, Wernberg T.   +6 more
europepmc   +1 more source