Results 91 to 100 of about 1,651,336 (303)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The American perception of the Turks an historical record

Milletleraras, 2000
Turkish-American diplomatic relaions, since ils foundation in the firsthalf of the ninelecnlh century, was conducted within a friendly atmosphere.Two counlries never enlered into wars with each other, or became membersof opposing alliances. Trade relations, too, flourished during the nineteethand early twentieeth centuries; especially, Turkish ...
openaire   +2 more sources

First European interception of the brown fir longhorn beetle, Callidiellum villosulum (Fairmaire, 1900) (Coleoptera, Cerambycidae) [PDF]

, 2013
A specimen of the brown fir longhorn beetle, Callidiellum villosulum villosulum found in Malta represents the first record of this invasive species for Europe.
Cocquempot, Christian, Mifsud, David
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Conference Review: Fifth International Congress of Experimental Archaeology, Tarragona (Spain), October 2017

EXARC Journal, 2018
Experimental archaeology is an important methodological resource for academic and historical scientific research, not separated from the rest of archaeological and historical sciences, and usually used to interpret the formation of the archaeological ...
Francesca Romagnoli, Javier Baena Preysler   +1 more
doaj  

Historical rainstorm in Hong Kong on 7–8 September 2023: Diagnosis, forecasting and nowcasting

Atmospheric Science Letters
On 7–8 September 2023, Hong Kong was hit by a historical and record‐breaking rainstorm associated with the remnant of Tropical Cyclone Haikui (2311).
Hiu Ching Tam, Yu‐Heng He, Pak Wai Chan, Shiwei Yu, Huisi Mo, Hui Su, Ling‐Feng Hsiao, Yangzhao Gong   +7 more
doaj   +1 more source

Strathconon, Scatwell and the Mackenzies in the Written Record c. 1463-c.1700 [PDF]

, 2010
Although some writers have considered the earlier history of Ross, these studies tend to focus on dynastic and political events and not much is know about the internal workings of Ross-shire far less Strathconon in the historical record prior to the end ...
Maccoinnich, Aonghas
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A large unknown historical earthquake in the Abruzzi region (Central Italy): combination of geological and historical data

Annals of Geophysics, 1995
The combination of paleoseismological and historical investigation can be used to obtain a complete knowledge of past earthquakes. In Italy the 1000 year-long record of historical earthquakes provides an opportunity to compare data from the catalogue ...
D. Pantosti, F. R. Cinti, G. D'Addezio
doaj   +1 more source

Retirement Withdrawal Rates and Portfolio Success Rates: What Can the Historical Record Teach Us? [PDF]

Countless current and prospective retirees now rely on portfolio success rates calculated from the historical data for different retirement withdrawal strategies when planning their own retirements.
Pfau, Wade Donald
core   +1 more source