Results 111 to 120 of about 54,538,745 (285)

Institute of Historical Research Annual Report 2004-5 [PDF]

, 2005
The IHR produces a report each year outlining its main activities and achievements. This is the report for academic year 2004-
Institute of Historical Research
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Sociopolitical development of the nursing profession in Iran: a historical review

Journal of Medical Ethics and History of Medicine, 2016
Significant sociopolitical changes in recent decades have not only influenced the nursing profession, but also the entire Iranian healthcare system. This study describes the historical evolution of the nursing profession within a sociopolitical context.
Afsaneh Raiesifar, Mohammadreza Firouzkouhi, Marjaneh Fooladi, Soroor Parvizy   +3 more
doaj  

Tracing the Decisions That Shaped the Development of MyChart, an Electronic Patient Portal in Alberta, Canada: Historical Research Study. [PDF]

J Med Internet Res, 2020
Avdagovska M, Stafinski T, Ballermann M, Menon D, Olson K, Paul P.   +5 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Historical research for higher degrees in the United Kingdom. Part 1: Theses completed.

Voortzetting van: Historical research for university degrees in the United Kingdom.
University of London. Institute of historical research
core  

Mapping and Spatiotemporal Analysis of Landslides Along the Costa Viola Transportation Network (Italy)

GeoHazards
Rainfall-induced landslides represent one of the most recurrent geohazards affecting the transportation network of southwestern Calabria (Italy). This study provides an integrated assessment of landslide occurrence and road damage along the Costa Viola ...
Massimo Conforti, Olga Petrucci
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Application of methods in historical nursing research

Pielęgniarstwo XXI Wieku
APPLICATION OF METHODS IN HISTORICAL NURSING RESEARCH Introduction. The article discusses the application of historical methods in nursing research. Aim.
Vladimira Pospisilova, Valérie Tóthová   +1 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source