Results 141 to 150 of about 2,470,978 (359)

Deep Mapping Uncertain Historical Sources

open access: yesJournal for the History of Knowledge
This article navigates through the challenge of preserving and presenting uncertainties in digital maps, which are used to reconstruct practical knowledge in early modern artists’ businesses. It introduces a novel methodology—deep mapping—as a multi-layered spatial visualization within the Geographical Information Systems (GIS).
openaire   +2 more sources

The Abbasid translation movement in context : contemporary voices on translation [PDF]

open access: yes, 2010
Over the decades, an enormous amount of scholarly work has been devoted to the historical and literary context of the Greek-Arabic translations. Without it, we would not be able to answer vital questions about dating and translators.
Vagelpohl, Uwe
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Features of the Term "Boktag" Semantic Component

open access: yesАрхеология евразийских степей
The article deals with the result of the analysis of various lexical names of "boktag" according to various sources. Having studied a number of modern publications, the author has identified more than ten names of this headdress.
Lyudmila E. Maklasova
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

THE POSSIBILITY OF AND POTENTIAL FOR THE MISCLASSIFICATION OF PROFESSIONAL ACCOUNTANTS IN ANTIQUITY [PDF]

open access: yes
The role of accounting functionaries in antiquity is of interest from the standpoint of the source documents used, reports generated, duties performed, and the requisite knowledge to perform established duties.
Stanley C. W. Salvary
core  

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