Results 31 to 40 of about 202,374 (316)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

Entre flores e canhões na Grande Guerra (1914-1918): o final da Belle Époque e o começo do "breve século XX" em um álbum de retratos fotográficos Between flowers and cannons in the Great World War (1914-1918): the end of Belle Époque and the beginning of the "Brief 20th Century" in an album of portraits

Revista Brasileira de História, 2009
O trabalho analisa oito retratos fotográficos pertencentes a um álbum de família alemão, sete dos quais datados dos tempos da Primeira Guerra Mundial (1914- 1918).
Marco Antonio Stancik
doaj   +1 more source

What has not yet been said about Prussian proper names in Polish lands

Vilnius University Open Series, 2022
The research of historical proper names reveals the necessity to emphasize and link the cultural, social and political aspects that play a role in the development of onyms.
Grasilda Blažienė
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

From Hermeneutics to Data to Networks: Data Extraction and Network Visualization of Historical Sources

The Programming Historian, 2015
Network visualizations can help humanities scholars reveal hidden and complex patterns and structures in textual sources. This tutorial explains how to extract network data (people, institutions, places, etc) from historical sources through the use of ...
Marten Düring
doaj  

Velhas e novas relações entre os medievalistas e suas fontes Old and new relations between medievalists and their sources

Varia História, 2010
O enfoque desse artigo é a maneira como os medievalistas hoje se relacionam com seus documentos na prática cotidiana do seu ofício e, mais particularmente, os desafios e as dificuldades enfrentadas, em particular, por aqueles interessados em temáticas ...
Dulce Oliveira Amarante dos Santos
doaj   +1 more source

‘By Your Mercy I Used to Live Quietly. What to Do? Please, Arbitrate, Your Grace’: Revisiting the Beginnings of 1723 Political Crisis in Kalmyk Khanate

Oriental Studies, 2022
Introduction. The article publishes one of the last letters submitted by Khan Ayuka of the Kalmyks to the Russian Emperor Peter the Great. Goals. The work aims at introducing newly discovered correspondence dealing with Russian-Kalmyk relations in the ...
Vladimir T. Tepkeev
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A prototype HGIS for managing earthquake data from historical documents

Geomatics, Natural Hazards & Risk, 2019
Studies regarding historical seismic events occurred during the pre-instrumental era are mostly based on the interpretation of coeval records reporting earthquake effects on humans and buildings as experienced and reported by witnesses.
Federica Migliaccio, Mario Locati, Daniela Carrion, Livia Manenti, Marco Martoccia   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source