Results 21 to 30 of about 166,704,379 (307)
Theories of social constructivism in Anglophone historical epistemology in 2000-2015
Social constructionism can be seen as a source of the postmodern movement, and has been influential in the field of cultural studies. The article is devoted to the analysis of the influence of social constructionism in modern Anglophone historiography ...
Ageeva Vera
doaj +1 more source
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
When worldviews or claims to knowledge become widely accepted and increasingly ossified, this demands the mobilization of critical reflection. It is to be expected that such claims have achieved the status of received wisdom because they serve the interests of some groups, skew power relations, and assist in reaffirming the geopolitical status quo ...
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Historical Psychology as the History of Psychological Knowledge
The article considers pre-modern psychological knowledge as a phenomenon of culture and mentality, namely, in the context of historical psychology, the science which studies the development of an individual and his/her personality in history.
Владимир Александрович Шкуратов
doaj +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
The Strategies of Systematization of the Theories of Education. The Main Meaning and Features of the Theories of Education of Plato’s and Isocrates’ Lines [PDF]
The article deals with the historical and philosophical analysis of scientific and philosophical ideas, which have influenced the development of the theories of The article deals with the historical and philosophical analysis of scientific and ...
Oleg Bazaluk
doaj

