Results 51 to 60 of about 48,093 (259)

Do museums heal wounds or perpetuate pain? Perceived implications for post-conflict peace-building in a Southeast Asian country

Rozprawy Społeczne
This study explores how the Public perceives historical narratives, particularly in relation to politics, generational differences, and trust in institutions such as museums.
Mark Gabriel Wagan Aguilar
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The Indigenous Historical Trauma of Naga Society and Its Musical Manifestations

Muzikološki Zbornik
Drawing on theories of historical trauma and colonial trauma, this article discusses the cumulative impact of colonial and postcolonial conflict, Christian proselytization, and Westernization on the societies, cultures, and songs of the Nagas, a South ...
Christian Poske
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Exploring the influence of trauma on ethical theory understanding: a narrative literature review based on public administration education

Frontiers in Education
This paper explores the intersection of trauma, ethics, and public administration pedagogy, focusing on the impact of intergenerational trauma on students’ comprehension and application of ethical theories in post-colonial contexts such as South Africa ...
Sibongile Ruth Nhari, Charlotte Taka, Thokozani Ian Nzimakwe   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Illness beyond the Scottish National Imaginary: Anorexia and Scots-Italian Historical Trauma in Andrew O’Hagan’s Personality

Études Écossaises
Madness and altered psychological states are prominent themes in Scottish literature and criticism. However, many forms of mental distress do not fit the national imaginary and are therefore under-researched. This article discusses two such health issues,
Fred Spence
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Mental health in the Kurdistan Region of Iraq

BJPsych International
The Kurdistan Region of Iraq (KRI) is a semi-autonomous region within the federal Iraq, governed by its own regional government. The Ministry of Health (MoH) is responsible for overseeing healthcare services and their regulation.
Dyari S. Hama amin, Aland A. Mustafa, Evan H. Aziz   +2 more
doaj   +1 more source