Results 31 to 40 of about 13,072 (311)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Bleeding Panels, Leaking Forms: Reading the Abject in Emily Carroll’s Through the Woods (2014)
The Comics Grid: Journal of Comics Scholarship, 2020 Seeking to move beyond Scott McCloud’s spatio-temporal reading of the bleed (1993: 103), this article explores how Canadian writer/artist Emily Carroll’s graphic narrative Through the Woods (2014) employs the bleed as a means to give form to a mode of ...
Miranda Jane Corcoran
doaj +2 more sources
Effects of Frequency, Temperature and Test Duration in the Viscoelasticity of Brazilian Hardwoods Used in Handmade Musical Instruments [PDF]
Materials Research, 2019 This study aims to make a comprehensive analysis on the viscoelastic behavior of typical tropical hardwoods and its influences in making musical instruments. For that a Dynamic-Mechanical Analysis was done and the mechanical parameters dependence on test
Júlio Ortiz Amando de Barros +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Tree-rings mirror management legacy: dramatic response of standard oaks to past coppicing in Central Europe. [PDF]
PLoS ONE, 2013 BackgroundCoppicing was one of the most important forest management systems in Europe documented in prehistory as well as in the Middle Ages. However, coppicing was gradually abandoned by the mid-20(th) century, which has altered the ecosystem structure,
Jan Altman +7 more
doaj +1 more source
Fracture behaviour of historic oak wood
, 2016 Damage that might originate from climate fluctuations can be observed on decorated oak wooden panels in historical Dutch cabinets and panel paintings. A thorough analysis of the damage mechanisms is needed to obtain a comprehensive understanding of the causes of damage and to develop sustainable conservation strategies.
Luimes, R.A. +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source