Results 151 to 160 of about 2,319 (266)

Risk–Benefit of Phase 2 Monotherapy Trials in Adult Solid Cancers: A Systematic Review and Meta‐Analysis

International Journal of Cancer, EarlyView.
The therapeutic status of drug administration in phase 2 cancer trials is ambiguous, as these studies test efficacy without strong evidence of clinical benefit. Nonetheless, patients face meaningful risks. This review compared efficacy and safety of monotherapy drugs in phase 2 and phase 3 trials across six cancer types.
Charlotte Ouimet, Monica Rosu, Jonathan Kimmelman   +2 more
wiley   +1 more source

Restorative environments and humanized practice in oncology services. [PDF]

Rev Bras Med Trab
Fernandes HMA, Lima ICS, Borges LS, Sampaio JJC.   +3 more
europepmc   +1 more source

Membranous dysmenorrhea and decidual casts: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Membranous dysmenorrhea, characterized by the expulsion of intact endometrial tissue rather than gradual dissolution during menstruation, occasionally presents as a decidual cast—a complete triangular mold of the uterine cavity. This poorly understood condition is likely underdiagnosed.
Lovisa Brehmer, Hedvig Engberg
wiley   +1 more source

Nursing and Pluralism: The Work of Michel Serres. [PDF]

Nurs Philos
McCaffrey G.
europepmc   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

iNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

Beyond Mechanism-Extending Our Concepts of Causation in Neuroscience. [PDF]

Eur J Neurosci
Potter HD, Mitchell KJ.
europepmc   +1 more source

Realistic Representation, Dynamic Evolution and Determinants of Institutional Quality in China

International Studies of Economics, EarlyView.
ABSTRACT The paper delves into the role of institutional quality in bolstering China's economic resilience post‐COVID‐19, CITIC‐Entropy. It divides institutions into basic and changeable categories, establishing an index system via the CITIC‐Entropy TOPSIS model.
Susu Wang, Qidi Zhang, Jing Fang
wiley   +1 more source

Colorectal cancer as a complex adaptive system: integrating the hallmarks of cancer with complexity theory. [PDF]

Front Oncol
Basbus LR.
europepmc   +1 more source

The Relevance of Apology to Reparations for Historical Injustice

Journal of Applied Philosophy, EarlyView.
ABSTRACT This article explains the centrality of apology to an adequate account of reparations. I look in depth at what goes on in apology. As I have previously argued, apology is an expressive action through which we seek to mark adequately the significance of our own wrongdoing. I claim that apology so understood is not merely ornamental.
Christopher Bennett
wiley   +1 more source

No Apologies? The Role of Apology for Structural‐Historical Injustice

Journal of Applied Philosophy, EarlyView.
ABSTRACT During this era of political apologies, a new literature has emerged in historical injustice interrogating the relationship between structural and historical injustice, with various theories conceptualising the relationship in different ways. Interestingly, ‘apology’ rarely appears in this literature.
Maeve McKeown
wiley   +1 more source