Results 101 to 110 of about 18,606,848 (387)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Facilitating high throughput collections-based genomics: a comparison of DNA extraction and library building methods

open access: yesScientific Reports
While DNA barcoding methods are an increasingly important tool in biological conservation, the resource requirements of constructing reference libraries frequently reduce their efficacy.
William A Marsh   +3 more
doaj   +1 more source

The Early Iron Age Treasure from Brașov [PDF]

open access: yesPeuce, 2015
This paper presents a recently found gold treasure discovered near the city of Braşov, dated to Hallstatt B1 and containing 22 gold notched Brăduţ-type rings.
Alexandra ȚÂRLEA   +4 more
doaj  

On Digital History

open access: yesBMGN - Low Countries Historical Review, 2013
Digital humanities seem to be omnipresent these days and the discipline of history is no exception. This introduction is concerned with the changing practice of ‘doing’ history in the digital age, seen within a broader historical context of developments in the digital humanities and ‘digital history’.
openaire   +8 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Roman History

open access: yesGreece and Rome, 2018
The first time I visited Pompeii, I was walking along one of its iconic paved streets when another visitor in front of me stumbled over a rough patch of pavement. Looking down resentfully, she turned to her friend and said in an irritated tone, ‘Look at this! They really need to do something about these roads…’. If that sore-toed tourist had found Eric
openaire   +2 more sources

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