Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
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On the Life-History of a New Monophlebus from India, with a Note on that of a Vedalia predaceous upon it. With a few Remarks on the Monophlebinae of the Indian Region. [PDF]
E. P. STEBBING
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Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
The Structure of Man. An Index to His Past History . By Dr. R. Wiedersheim, Professor in the University of Freiburg in Baden. Translated by H. and M. Bernard. The Translation edited and annotated and a Preface written by G. B. Howes, F. L. S., Professor of Zoology, Royal College of Science, London. With 105 Figures in the Text. Macmillan & Co., London and New York. Price $2.60. [PDF]
Harrison Allen
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Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
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Postage on Natural History Specimens [PDF]
Isaac J. Wistar, Edw. J. Nolan
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TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
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On the power wisdom and goodness of God as manifested in the creation of animals and in their history habits and instincts. [PDF]
William Kirby
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