Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Inflammatory and Insulinemic Dietary Patterns and Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes Mellitus: A Prospective Study of 84,174 Person-Years of Follow-up. [PDF]
Liu P +7 more
europepmc +1 more source
Frontier Constellations: A History of Land-use Regimes in Paraguay’s Pilcomayo River Basin
Yann le Polain de Waroux
openalex +2 more sources
Age Adjustment of Production Records: History and Basic Problems
A.E. Freeman
openalex +1 more source
Cottons Consumption In The Seventeenth- And Eighteenth-Century North Atlantic [PDF]
DuPlessis, Robert S.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Analyzing the "Opposite" Approach in Additions to Historic Buildings Using Visual Attention Tools: Dresden Military History Museum Case. [PDF]
Özkaraca Özalp N +3 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Review Of Education And Middle-Class Society In Imperial Austria, 1848-1918 By G.B. Cohen [PDF]
Judson, Pieter M., , \u2778
core +1 more source

