Results 251 to 260 of about 15,133,243 (346)

The Pogrom Of 1905 In Odessa: A Case Study [PDF]

, 1992
Weinberg, Robert
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Influence of immune history when choosing a SARS-CoV-2 booster strategy. [PDF]

Sci Rep
Larsen SL, Noor I, West H, Chandra E, Martinez PP, Kraay ANM.   +5 more
europepmc   +1 more source

A Centennial History of the University of Louisville.

, 1940
Charles Smith, Kentucky Writers'
openalex   +2 more sources

The Body In Question: Review Of The Anatomy Of Power: European Constructions Of The African Body By A. Butchart [PDF]

, 1999
Burke, Timothy
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Developing core indicators for identifying people at risk of delayed heart failure diagnosis. [PDF]

BMC Prim Care
Barber K, Bernhardt L, McCann GP, Squire I, Miller CA, Deaton C, Khunti K, Lawson CA.   +7 more
europepmc   +1 more source

Publisher Correction: Facilitating high throughput collections-based genomics: a comparison of DNA extraction and library building methods

Scientific Reports
William A. Marsh, Andie Hall, Ian Barnes, Ben Price   +3 more
doaj   +1 more source

Transatlantic Textiles: European Linen In The Cloth Cultures Of Colonial North America [PDF]

, 2003
DuPlessis, Robert S.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source