Results 261 to 270 of about 15,622,689 (344)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Psychiatric Comorbidities and Sociodemographics of Patients Diagnosed with Pyromania Admitted to a Community Psychiatric Hospital in Bronx, New York: Retrospective Chart. [PDF]

Indian J Psychol Med
Joshaghani N, Sharma V, Taneja G, Jiménez-Parrado LD, Hartnett R, Mitra S, Gunturu S.   +6 more
europepmc   +1 more source

Curation history and mineralisation of highly degraded pyrite fossil collection [PDF]

, 2004
Emily S. Hodgkinson, Susan Martin
openalex  

HYDANTOINS: THE HISTORY OF 2-THIOHYDANTOIN. XXII.

, 1913
Treat B. Johnson
openalex   +2 more sources

Eyes Wide Shut: Africanists And The Moral Problematics Of Postcolonial Societies [PDF]

, 2003
Burke, Timothy
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Early recurrence of febrile seizures during acute illness: risk factors and lack of association with long-term epilepsy in a Pediatric cohort. [PDF]

Front Neurol
Jiang W, Cheng A, Wang J, Wang R, Zhang S, Huang Y.   +5 more
europepmc   +1 more source

Publisher Correction: Facilitating high throughput collections-based genomics: a comparison of DNA extraction and library building methods

Scientific Reports
William A. Marsh, Andie Hall, Ian Barnes, Ben Price   +3 more
doaj   +1 more source

Review Of Colonial Psychiatry And \u27The African Mind\u27 By J. McCulloch [PDF]

, 1996
Burke, Timothy
core   +1 more source