Results 71 to 80 of about 18,606,848 (387)

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Top Incomes in the Long Run of History

, 2009
A recent literature has constructed top income shares time series over the long run for more than twenty countries using income tax statistics. Top incomes represent a small share of the population but a very significant share of total income and total ...
A. Atkinson, T. Piketty, Emmanuel Saez
semanticscholar   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

ZoologyCon 2024 - Book of Abstracts [PDF]

Travaux du Muséum National d’Histoire Naturelle “Grigore Antipa”
The book contains the abstracts and program of the international zoological congress ZOOLOGYCON 2024, organized by the Grigore Antipa Museum and held in Bucharest, Romania from 6th to 9th November 2024.
Luis Ovidiu Popa, Costică Adam, Maxim-Jean Bâlcu, Andreea Maria Brezeanu, Ioana Cristina Constantinescu, Larisa Bianca Farcaș, Ana-Maria Krapal, Rozalia Magda Motoc, Alexandra Popa, Oana Paula Popa, Florentina Purdescu, Melania Stan, Andrei Ștefan   +12 more
doaj   +3 more sources

Development and application of an electronic treatment register: a system for enumerating populations and monitoring treatment during mass drug administration

Global Health Action, 2020
We developed an electronic treatment register for the DeWorm3 Project, a cluster-randomised, controlled trial in Benin, India, and Malawi testing the feasibility of interrupting transmission of soil-transmitted helminths through community-wide mass drug ...
William E. Oswald, David S. Kennedy, Jasmine Farzana, Saravanakumar Puthupalayam Kaliappan, Eloic Atindegla, Parfait Houngbégnon, Alvin Chisambi, Stefan Witek-McManus, Sean R. Galagan, Mira Emmanuel-Fabula, Marie-Claire Gwayi-Chore, Hugo Legge, Elodie Yard, Khumbo Kalua, Moudachirou Ibikounlé, Sitara Swarna Rao Ajjampur, Arianna Rubin Means, Kristjana H. Ásbjörnsdóttir, Katherine E. Halliday, Judd L. Walson   +19 more
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

A prospective natural-history study of coronary atherosclerosis.

New England Journal of Medicine, 2011
BACKGROUND Atherosclerotic plaques that lead to acute coronary syndromes often occur at sites of angiographically mild coronary-artery stenosis. Lesion-related risk factors for such events are poorly understood.
G. Stone, A. Maehara, A. Lansky, B. de Bruyne, Ecaterina Cristea, G. Mintz, R. Mehran, J. Mcpherson, Naim Z. Farhat, S. Marso, H. Parise, B. Templin, Roseann M. White, Zhen Zhang, P. Serruys   +14 more
semanticscholar   +1 more source

Conceptual History, Cultural History, Social History

ВИВЛIОθИКА: E-Journal of Eighteenth-Century Russian Studies, 2014
V. M. Zhivov’s introduction to Studies in Historical Semantics of the Russian Language in the Early Modern Period (2009), translated here for the first time, offers a critical survey of the historiography on Begriffsgeschichte, the German school of conceptual history associated with the work of Reinhart Koselleck, as well as of its application to the ...
openaire   +5 more sources

History Repeating?

Journal of the American College of Cardiology, 2017
We read with interest the paper by Seitz et al. [(1)][1] focusing on mapping areas of spatiotemporal electrogram dispersion in patients with atrial fibrillation (AF). According to the authors, these areas represent “AF drivers” and their ablation is a personalized, more effective strategy ...
Gianni C, Mohanty S, Di Biase L, Natale A   +3 more
openaire   +3 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source