Results 61 to 70 of about 679,922 (236)

Revisiting Nurse Rivers

Voices in Bioethics, 2013
The Tuskegee syphilis study’s most enduring figure is also one of its most intriguing. Nurse Eunice Rivers was instrumental to the study for both procuring its members and then keeping them involved in it.
Lisa Kearns
doaj   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

The need for philosophical education in contemporary society [PDF]

Place of philosophy in the contemporary world seems condemned to be an ongoing archeology of the mind, which can produce something new only epigonic reliving the great moments of its own history.
Ph.D. Antonio SANDU
core   +1 more source

Analytic Metaphysics versus Naturalized Metaphysics: The Relevance of Applied Ontology [PDF]

, 2018
The relevance of analytic metaphysics has come under criticism: Ladyman & Ross, for instance, have suggested do discontinue the field. French & McKenzie have argued in defense of analytic metaphysics that it develops tools that could turn out to be ...
A Barton, A Bryant, A Mitrovic, AD Spear, Adrien Barton, B Bihan Le, B Smith, B Smith, B Smith, B Smith, Baptiste Le Bihan, C Rosse, D Lewis, D Mark, D Wallace, DJ Baker, E Sirin, H Halvorson, J Benovsky, J Benovsky, J Earman, J Ladyman, J Röhl, J-F Ethier, JF Ethier, K Grill, L Jansen, M Dorato, M Esfeld, N Guarino, N Huggett, N Lambert, O Pooley, P Grenon, R Arp, R Poidevin Le, S French, S French, S Mumford   +38 more
core   +5 more sources

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

“Thanatopolitics” in the Socio-Political Discourse in the 2000s and 2020s: between the “Living Dead” and “Necrosociality”

Дискурс
Introduction. Over the past twenty years, the terms “thanatopolitics”, “necropolitics”, “necroeconomics”, etc. have been actively used in socio-political discourse. But the definitions of these meanings remain blurred.
I. M. Rotov
doaj   +1 more source

Practice-oriented controversies and borrowed epistemic credibility in current evolutionary biology: phylogeography as a case study [PDF]

, 2013
Although there is increasing recognition that theory and practice in science are intimately intertwined, philosophy of science perspectives on scientific controversies have been historically focused on theory rather than practice.
Arroyo-Santos, Alfonso, Olson, Mark E., Vergara-Silva, Francisco   +2 more
core   +3 more sources

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi, Sunghoon Lee, Tomoyuki Yokota, Takao Someya   +3 more
wiley   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

AP‐Lab: An AI‐Driven Autonomous Pilot‐Scale Platform Bridging Materials Discovery and Industrial Manufacturing

Advanced Science, EarlyView.
AP‐Lab bridges materials discovery and industrial manufacturing by coupling proprietary datasets with an application benchmark (PCR Ct). A closed‐loop optimization workflow integrates ML, LLM, and autonomous synthesis/testing to refine magnetic nanoparticles–based nucleic‐acid extraction systems.
Zhan‐Long Wang, Zhifen Ma, Wenxing Song, Guolai Jiang, Boshi Jiang, Mingyang Jiang, Weiliang Shu, Bing Wang, Zhiyuan Wan, Shengyong Geng, Zhen Zhao, Wenhua Zhou, Xue‐Feng Yu   +12 more
wiley   +1 more source