Results 171 to 180 of about 1,013,070 (269)

100 years International Council of Ophthalmology. [PDF]

Int J Ophthalmol
Wiedemann P.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Cervical cancer screening willingness and associated health beliefs among predominantly college-educated young women attending gynecology clinics in Shenzhen, China. [PDF]

Front Public Health
Li H, Ke Y, Wu M, Shen L, Jiang N, Wang H, Wang M, Qiu X, Wu Q, Bai H, Wang Y, Gao Y, Cao W, Zhang Y.   +13 more
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

How Endpoint Definitions Shape Epidemiologic Inference on Tuberculosis Treatment Outcomes: A Secondary Analysis from Lima, Peru. [PDF]

Infect Dis Rep
Vera-Ponce VJ, Ballena-Caicedo J, Cervera Vasquez NJ, García-Rodríguez MD, Yumpo Ynga JA, Zuzunaga-Montoya FE.   +5 more
europepmc   +1 more source

History of Computing in Education [PDF]

, 2004
openaire   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Effect of Family Medical History of Hypertension and Its Interaction with Diabetes on an Additive Scale on the Diagnosis of Hypertension Among Middle-Aged and Older Adults in India: Longitudinal Ageing Study in India. [PDF]

Healthcare (Basel)
Al Jowf GI, Ahmed W.
europepmc   +1 more source