Results 71 to 80 of about 7,613,950 (298)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Rusalies: The Testimony of Byzantine Tradition

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2014
The festival of rusalies is one of the paganism relics in the medieval Byzantium. It was the subject of numerous special studies, where Byzantine traditions unfortunately recede to the background. The modern scientific summaries disregard the information
VIN Yu.Ya.
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

“The struggle for universal peace” or “the deception policy”: The issue of international arbitration in American-German relations on the eve of the First World War. 1904–1914

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки
Importance. The problem of resolving military conflicts by peaceful means has attracted and continues to attract the attention of not only professional historians, but also broadest sectors of civil society.
V. K. Shatsillo
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

MUNZUR DAĞLARI ALT MİYOSEN ÇÖKELLERİ MOLLUSK TOPLULUĞU VE PALEOEKOLOJİSİ (DOĞU ANADOLU, TÜRKİYE)

open access: yesBulletin of the Mineral Research and Exploration, 2017
Araştırma konusu, Tunceli ili Ovacık ilçesinde yer alan Munzur Dağlarında yüzlek veren Miyosen yaşlı birimlerdir. Munzur Dağlarında Paleozoik’ten Senozoik’e kadar devam eden bir çökelim bulunmaktadır.
Müjde GÜRSOY
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

ASTRONAUT SELECTION AND POTENTIAL RISK MANAGEMENT: PSYCHOLOGICAL TRAUMA AND RESILIENCE FOR MARS SPACE MISSION [PDF]

open access: yesTrames
The first human orbited the Earth for less than two hours in 1961. The twelve Apollo astronauts experienced up to 22 hours of walking on the Moon (Apollo 17).
David W. Kim
doaj   +1 more source

Reconstructing the Star Formation History of the Galaxy

open access: yes, 2000
The evolution of the star formation rate in the Galaxy is one of the key ingredients quantifying the formation and determining the chemical and luminosity evolution of galaxies.
CC Lin   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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