Results 81 to 90 of about 17,748,027 (382)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Rusalies: The Testimony of Byzantine Tradition
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2014 The festival of rusalies is one of the paganism relics in the medieval Byzantium. It was the subject of numerous special studies, where Byzantine traditions unfortunately recede to the background. The modern scientific summaries disregard the information
VIN Yu.Ya.
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
ASTRONAUT SELECTION AND POTENTIAL RISK MANAGEMENT: PSYCHOLOGICAL TRAUMA AND RESILIENCE FOR MARS SPACE MISSION [PDF]
TramesThe first human orbited the Earth for less than two hours in 1961. The twelve Apollo astronauts experienced up to 22 hours of walking on the Moon (Apollo 17).
David W. Kim
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The production of ideas: Notes on Austrian intellectual history from Bolzano to Wittgenstein [PDF]
, 1981 This paper takes the form of a series of sketches of 19th century Austrian political and intellectual history, allied with a number of more general reflections designed to contribute to our understanding of some of the peculiar characteristics of ...
Smith, Barry
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
MUNZUR DAĞLARI ALT MİYOSEN ÇÖKELLERİ MOLLUSK TOPLULUĞU VE PALEOEKOLOJİSİ (DOĞU ANADOLU, TÜRKİYE)
Bulletin of the Mineral Research and Exploration, 2017 Araştırma konusu, Tunceli ili Ovacık ilçesinde yer alan Munzur Dağlarında yüzlek veren Miyosen yaşlı birimlerdir. Munzur Dağlarında Paleozoik’ten Senozoik’e kadar devam eden bir çökelim bulunmaktadır.
Müjde GÜRSOY
doaj +1 more source
, 1958 Vastly increased research and a sounder technique in history in the nineteenth century had two influences on the social sciences. When an enthusiasm for the records of history was combined with the evolutionary perspective, it often resulted in the ...
Bloom, Robert L. +6 more
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