Results 91 to 100 of about 1,980,833 (368)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Legal incapacitation in media access interdictions and the internet [PDF]

open access: yes, 2016
In this paper I first situate the general norm in the Council of Europe countries on access to the internet by actors in the media in the context of key concerns related to the internet as a medium according to UNESCO’s Internet Study.
Wiersma, Chris
core   +2 more sources

Europe: Institutional structure for security since the Peace of Westphalia / Europa: Estructura institucional para la seguridad desde la Paz de Westfalia

open access: yesBarataria, 2008
The present work seeks to carry out a succinct revision of the most significant events in the long historical process that have determined the institutional structure for the security in Europe from the Peace of Westphalia.
Francisco José Blanco Jiménez   +1 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Strange Parallels: Patterns in Eurasian Social Evolution

open access: yesJournal of World-Systems Research, 2015
Most professional historians have abandoned the search for general patterns and laws of history, but not Victor Lieberman. Strange Parallels II (SP II), following on SP I, proposes that similar mechanisms governed state building in such different, and ...
Peter Turchin
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Literární komparatistika, areálová/kulturní studia, teorie literárních dějin a problém hodnoty v současné literárněvědné praxi

open access: yesOpera slavica, 2013
The author of the present study deals with the crucial and topical problems concerning both the comparative studies and area/cultural studies as we ll as the history and theory of national literatures and the comparative studies and their methodology in ...
Ivo Pospíšil
doaj  

American-European Relations in U. S. World History Textbooks, 1921-2001

open access: yesAmerican Studies in Scandinavia, 2012
This article studies U.S. views of the historical relationship between the U.S. and Europe as conceived during the 20th century. This is examined through U.S. World history text books dating from 1921 to 2001.
Martin Alm
doaj   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Text types in a new medium : the first newspapers (1609) [PDF]

open access: yes, 2009
The first printed newspapers in the modern sense of the word appeared in the seventeenth century. They were weekly publications which contained regular reports by correspondents from all over Europe, mainlyon political matters. Although the new medium as
Fritz, Gerd
core  

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