Results 91 to 100 of about 2,099,771 (306)

Strange Parallels: Patterns in Eurasian Social Evolution

open access: yesJournal of World-Systems Research, 2015
Most professional historians have abandoned the search for general patterns and laws of history, but not Victor Lieberman. Strange Parallels II (SP II), following on SP I, proposes that similar mechanisms governed state building in such different, and ...
Peter Turchin
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

American-European Relations in U. S. World History Textbooks, 1921-2001

open access: yesAmerican Studies in Scandinavia, 2012
This article studies U.S. views of the historical relationship between the U.S. and Europe as conceived during the 20th century. This is examined through U.S. World history text books dating from 1921 to 2001.
Martin Alm
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Population ecology of an alien “warm water” crayfish (Procambarus clarkii) in a new cold habitat

open access: yesKnowledge and Management of Aquatic Ecosystems, 2011
Procambarus clarkii is one of the worst invasive and best-studied crayfish species worldwide, but its life history at higher latitudes is poorly understood. In the present study, the population ecology of P.
Chucholl C.
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The geographic spread of the CCR5 Delta32 HIV-resistance allele.

open access: yesPLoS Biology, 2005
The Delta32 mutation at the CCR5 locus is a well-studied example of natural selection acting in humans. The mutation is found principally in Europe and western Asia, with higher frequencies generally in the north.
John Novembre   +2 more
doaj   +2 more sources

Lalkarz Jurkowski (1927–2016)

open access: yesPamiętnik Teatralny, 2016
Memory of Henryk Zdzisław Jurkowski (1927–2016), a puppet theatre historian, theorist and critic, pedagogue, dramatist, editor, and long-time Polish representative in UNIMA (Union Internationale de la Marionnette), officer of the Union’s governing bodies
Marek Waszkiel
doaj   +1 more source

Primary prevention of beta-cell autoimmunity and type 1 diabetes - The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives. [PDF]

open access: yes, 2016
OBJECTIVE: Type 1 diabetes can be identified by the presence of beta-cell autoantibodies that often arise in the first few years of life. The purpose of this perspective is to present the case for primary prevention of beta-cell autoimmunity and to ...
Agiostratidou, G   +8 more
core   +4 more sources

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou   +12 more
wiley   +1 more source

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